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. 2023 May;36(4):1071-1073.
doi: 10.1007/s40620-022-01487-7. Epub 2022 Dec 2.

Lack of predictive capacity of pre-transplant anti-BK virus antibodies for post-transplant reactivation

Arturo Blazquez-Navarro  1   2 , Toralf Roch  1   2 , Patrizia Wehler  1   2 , Ulrik Stervbo  1   2 , Chris Bauer  3 , Kerstin Wolk  4 , Robert Sabat  4 , Chantip Dang-Heine  2 , Oliver Thomusch  5 , Petra Reinke  6 , Christian Hugo  7 , Panagiota Zgoura  1   8 , Richard Viebahn  8 , Timm Westhoff  1 , Michal Or-Guil  9 , Nina Babel  10   11
Affiliations

Lack of predictive capacity of pre-transplant anti-BK virus antibodies for post-transplant reactivation

Arturo Blazquez-Navarro et al. J Nephrol. 2023 May.
No abstract available

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Conflict of interest statement

The authors have no conflicts of interest.

Figures

Fig. 1
Fig. 1
Pre-transplant reactive to the BKV VP1 are almost ubiquitous and are associated with pre-Tx BKV load and early viral reactivation. A Histogram of the distribution of pre-transplant anti-BKV antibodies. B Histogram of the distribution of peak BKV viral load during the first post-transplant year among patients with viral reactivation. Note the logarithmic scale of the x axis. C Comparison of pre-transplant anti-BKV antibody levels between patients with no BKV reactivation during the first post-transplant year and patients with BKV reactivation. Note the logarithmic scale of the y axis. D Scatterplot of anti-BKV antibody levels and peak BKV viral load during the first post-transplant year among patients with viral reactivation. Note the logarithmic scale of both axes. E Comparison of pre-transplant anti-BKV antibody levels between patients with no pre-transplant viral load and patients with pre-transplant BKV load. Note the logarithmic scale of the y axis. F Comparison of pre-transplant anti-BKV antibody levels between patients with BKV reactivation at an early and late time point. The categories early and late were defined with respect to the median reactivation time of 62 days post-transplant. Note the logarithmic scale of the y axis. G Scatterplot of anti-BKV antibody levels and graft function one year post-transplant. Note the logarithmic scale of the x axis. BKV BK virus; Pre-Tx pre-transplant, eGFR-1y estimated glomerular filtration rate 1 year post-transplant
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References

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