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Meta-Analysis
. 2023 Apr 23;38(2):305-308.
doi: 10.21470/1678-9741-2022-0002.

DEX, Delirium and Dilemma

Rohan Magoon  1 , Shalvi Mahajan  2 , Jes Jose  3
Affiliations
Meta-Analysis

DEX, Delirium and Dilemma

Rohan Magoon et al. Braz J Cardiovasc Surg. .

Abstract

Dexmedetomidine has been subjected to an extensive evaluation for its' role in the prevention of postoperative delirium following cardiac surgery. In striking contrast to the preexisting meta-analysis supporting postoperative delirium-reduction with dexmedetomidine, few recently concluded multicentric large scale randomized controlled trials suggest otherwise. This article aims to present a nuanced perspective of the evolving controversy by attempting to decode the apparent incongruences in the literature accumulating off-late, which is particularly pertinent amidst an ever-escalating heterogeneity in the current research ecosystem.

Keywords: Cardiac Surgery; Delirium; Dexmedetomidine; Meta-Analysis; Randomized Controlled Trials..

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Conflict of interest statement

No conflict of interest.

References

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