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Comment
. 2022 Dec 1;30(12):1563-1564.
doi: 10.1016/j.str.2022.11.005.

Tethering CST to the telomerase catalytic core-the p50 linchpin

Nithila A Joseph  1 , Liuh-Yow Chen  2
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Tethering CST to the telomerase catalytic core-the p50 linchpin

Nithila A Joseph et al. Structure. .
Free article

Abstract

Emerging models of telomere and associated proteins in Tetrahymena have broadened our understanding of telomeric processes. In this issue of Structure, Ma et al. pinpoint a region in p50 that associates with the CST complex. The interaction mediated by p50 is crucial for the optimal positioning of TERT to maintain homeostasis at the chromosome ends.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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