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. 2023 Dec;32(12):2623-2635.
doi: 10.1007/s00787-022-02116-1. Epub 2022 Dec 2.

How does Tourette syndrome impact adolescents' daily living? A text mining study

Cyril Atkinson-Clement  1   2 , Marion Duflot  3 , Eloise Lastennet  3 , Leïla Patsalides  3 , Emma Wasserman  3 , Therese-Marie Sartoris  3 , Clément Tarrano  3 , Charlotte Rosso  3   4 , Pierre Burbaud  5 , Emmanuelle Deniau  3   6 , Virginie Czernecki  3   6 , Emmanuel Roze  3 , Andreas Hartmann  3   6 , Yulia Worbe  3   6   7
Affiliations

How does Tourette syndrome impact adolescents' daily living? A text mining study

Cyril Atkinson-Clement et al. Eur Child Adolesc Psychiatry. 2023 Dec.

Abstract

Tourette syndrome is a neurodevelopmental disease in which clinical manifestations are essentially present during childhood and adolescence, corresponding to one of the critical development phases. However, its consequences on the daily lives of young patients have been insufficiently investigated. Here, we aimed to investigate this using a statistical text mining approach, allowing for the analysis of a large volume of free textual data. Sixty-two adolescents with Tourette syndrome participated in an interview in which they discussed their daily life (i) in school, (ii) at home, and (iii) with strangers, (iv) the aspect of Tourette syndrome which caused the most difficulty, and (v) their thoughts regarding their future as adults. Following data pre-processing, these corpora were analyzed separately using the IRAMUTEQ software through factorial correspondence analysis to identify the most commonly recurring topics of each corpus, and their relations with clinical features. The main difficulty corpus was directly related to comorbidities of Tourette syndrome. Daily life at home was correlated with executive functioning. Difficulties at school were related to a higher severity of tics. Thoughts regarding future daily life were worst for the youngest patients and were correlated with executive functioning and a higher depression score. Taken altogether, our results highlighted that social stigma was a pervasive topic among our corpora. From a clinical standpoint, tic severity was especially related to difficulties at school, while comorbidities had a high impact on social daily living and cost for managing both tics and symptoms of comorbidities. TRIAL REGISTRATION: clinicaltrials.gov/ct2/show/NCT04179435.

Keywords: Daily living; School; Stigma; Text mining.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Results on the main difficulty corpus
Fig. 2
Fig. 2
Results on the daily living at home corpus
Fig. 3
Fig. 3
Results on the daily living at school corpus
Fig. 4
Fig. 4
Results on the relation with strangers corpus
Fig. 5
Fig. 5
Results on the expectations regarding future corpus
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