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. 1978 Dec 22;202(4374):1257-60.
doi: 10.1126/science.364651.

Implications of RNA-RNA splicing in evolution of eukaryotic cells

Implications of RNA-RNA splicing in evolution of eukaryotic cells

J E Darnell Jr. Science. .

Abstract

The differences in the biochemistry of messenger RNA formation in eukaryotes compared to prokaryotes are so profound as to suggest that sequential prokaryotic to eukaryotic cell evolution seems unlikely. The recently discovered noncontiguous sequences in eukaryotic DNA that encode messenger RNA may reflect an ancient, rather than a new, distribution of information in DNA and that eukaryotes evolved independently of prokaryotes.

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