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Review
. 2022 Nov 28:19:101060.
doi: 10.1016/j.artd.2022.10.010. eCollection 2023 Feb.

Total Knee Arthroplasty Complicated by Diffuse Large B-Cell Lymphoma

Robert Wetzel  1 , Brian Palumbo  1 , Thomas L Bernasek  1   2 , Steven Lyons  1
Affiliations
Review

Total Knee Arthroplasty Complicated by Diffuse Large B-Cell Lymphoma

Robert Wetzel et al. Arthroplast Today. .

Abstract

A 74-year-old male with a prior left total knee arthroplasty presented with deformity, loosening, pain, and stiffness associated with multiple raised, erythematous, cutaneous nodules about the anterior knee. Workup was concerning for infection, but the skin nodules were atypical. The patient was sent for biopsy which revealed cutaneous diffuse large B-cell lymphoma. The revision surgery was delayed, and the patient underwent chemotherapy/radiation with complete resolution of his lymphoma. He then underwent a successful aseptic revision total knee arthroplasty. Proper identification and treatment of rare cutaneous skin lesions about a prior surgical site can limit morbidity and result in more desirable outcomes.

Keywords: Arthroplasty; Case report; Cutaneous skin lesions knee; Lymphoma.

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Figures

Figure 1
Figure 1
Anterior knee cutaneous nodules upon presentation to clinic.
Figure 2
Figure 2
Posterior-anterior and lateral radiographs of the left knee with valgus malalignment and lucency about the femoral component (implant: Stryker Triathlon TS).
Figure 3
Figure 3
Skin biopsy with sheets of lymphoid-type cells and diffuse nonepidermotropic lymphoid infiltrate (100x).
Figure 4
Figure 4
High power yielding hyperchromatic and enlarged lymphocytes.
Figure 5
Figure 5
Left knee after the completion of chemotherapy and radiation. Complete resolution of skin nodules and erythema.
Figure 6
Figure 6
Status after the revision surgery performed on the long-stemmed cemented femur.
See this image and copyright information in PMC

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