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Review
. 2022 Nov 28:15:6439-6451.
doi: 10.2147/JIR.S288294. eCollection 2022.

Topical Anti-Inflammatory Agents for Non-Infectious Uveitis: Current Treatment and Perspectives

Balini Balasubramaniam  1 , Yu Jeat Chong  2 , Matthew Azzopardi  3 , Abison Logeswaran  4 , Alastair K Denniston  1
Affiliations
Review

Topical Anti-Inflammatory Agents for Non-Infectious Uveitis: Current Treatment and Perspectives

Balini Balasubramaniam et al. J Inflamm Res. .

Abstract

Non-infectious uveitis represents a heterogenous group of immune-mediated ocular diseases, which can be associated with underlying systemic disease. While the initial choice of treatment of non-infectious uveitis depends on a number of factors such as anatomical location and degree of inflammation, topical therapies often remain the initial choice of non-invasive therapy. In this narrative review, we aim to describe the literature on non-infectious uveitis, with specific focus on the current perspective on topical anti-inflammatory therapy.

Keywords: non-infectious uveitis; topical anti-inflammatory therapy; topical corticosteroids; topical cycloplegics; topical non-steroid anti-inflammatory drugs.

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Conflict of interest statement

The authors report no conflicts of interest in this work.

Figures

Figure 1
Figure 1
Simplified anti-inflammatory pathways of glucocorticoids.
Figure 2
Figure 2
The anti-inflammatory effect of NSAIDs via the arachidonic acid pathway.,
See this image and copyright information in PMC

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