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. 2022 Nov 15:2022:10.17912/micropub.biology.000679.
doi: 10.17912/micropub.biology.000679. eCollection 2022.

Drosophila simulans - Ilp2

Leon F Laskowski  1 , Cole A Kiser  2 , Robyn Huber  3 , Sean Kusche  4 , Andrew M Arsham  3 , Thomas C Giarla  4 , Chinmay P Rele  2
Affiliations

Drosophila simulans - Ilp2

Leon F Laskowski et al. MicroPubl Biol. .
No abstract available

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
(A) Synteny comparison of the genomic neighborhoods for Ilp2 in Drosophila melanogaster and D. simulans . Thin underlying arrows indicate the DNA strand within which the target gene– Ilp2 –is located in D. melanogaster (top) and D. simulans (bottom). Thin arrow(s) pointing to the right indicate(s) that Ilp2 is on the positive (+) strand in D. simulans and D.melanogaster . The wide gene arrows pointing in the same direction as Ilp2 are on the same strand relative to the thin underlying arrows, while wide gene arrows pointing in the opposite direction of Ilp2 are on the opposite strand relative to the thin underlying arrows. White gene arrows in D. simulans indicate orthology to the corresponding gene in D. melanogaster . Gene symbols given in the D. simulans gene arrows indicate the orthologous gene in D. melanogaster , while the locus identifiers are specific to D. simulans . (B) Gene Model in GEP UCSC Track Data Hub (Raney et al ., 2014). The coding-regions of Ilp2 in D. simulans are displayed in the User Supplied Track (black); coding exons are depicted by thick rectangles and introns by thin lines with arrows indicating the direction of transcription. Subsequent evidence tracks include BLAT Alignments of NCBI RefSeq Genes (dark blue, alignment of Ref-Seq genes for D. simulans ), Spaln of D. melanogaster Proteins (purple, alignment of Ref-Seq proteins from D. melanogaster ), Transcripts and Coding Regions Predicted by TransDecoder (dark green), RNA-Seq from Adult Females and Adult Males (red and light blue, respectively; alignment of Illumina RNA-Seq reads from D. simulans ), and Splice Junctions Predicted by regtools using D. simulans RNA-Seq (Graveley et al. , 2011; SRP006203). Splice junctions shown have a read-depth of 50-99 supporting reads in green. (C) Dot Plot of Ilp2-PA in D. melanogaster ( x -axis) vs. the orthologous peptide in D. simulans ( y -axis). Amino acid number is indicated along the left and bottom; coding-exon number is indicated along the top and right, and exons are also highlighted with alternating colors. The boxes highlighted in red and yellow (Box Y; Box Z) indicate lack of sequence similarity between amino acids.
See this image and copyright information in PMC

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