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. 2023 Jan;61(1):106700.
doi: 10.1016/j.ijantimicag.2022.106700. Epub 2022 Dec 5.

Role of β-lactamase inhibitors on cefiderocol activity against carbapenem-resistant Acinetobacter species

Vyanka Mezcord  1 , Olivia Wong  1 , Fernando Pasteran  2 , Alejandra Corso  3 , Marcelo E Tolmasky  1 , Robert A Bonomo  4 , María Soledad Ramirez  1
Affiliations

Role of β-lactamase inhibitors on cefiderocol activity against carbapenem-resistant Acinetobacter species

Vyanka Mezcord et al. Int J Antimicrob Agents. 2023 Jan.
No abstract available

Keywords: Acinetobacter; NDM-1; PER; carbapenem-resistance; cefiderocol; diazabicyclooctanes (DBOs); sulbactam.

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Conflict of interest statement

Competing Interests: None to declare

References

    1. Paterson DL, Isler B, Stewart A. New treatment options for multiresistant gram negatives. Curr Opinion Infect Dis 2020;33:214–23 - PubMed
    1. Bassetti M, Echols R, Matsunaga Y, Ariyasu M, Doi Y, Ferrer R, et al. Efficacy and safety of cefiderocol or best available therapy for the treatment of serious infections caused by carbapenem-resistant Gram-negative bacteria (CREDIBLE-CR): a randomised, open-label, multicentre, pathogen-focused, descriptive, phase 3 trial. Lancet Infect Dis 2021;21:226–40. - PubMed
    1. Barnes MD, Kumar V, Bethel CR, Moussa SH, O’Donnell J, Rutter JD, et al. Targeting multidrug-resistant Acinetobacter spp.: Sulbactam and the diazabicyclooctenone beta-lactamase inhibitor ETX2514 as a novel therapeutic agent. mBio 2019;10 e00159–19 - PMC - PubMed
    1. Pasteran F, Cedano J, Baez M, Albornoz E, Rapoport M, Osteria J, et al. A new twist: The combination of sulbactam/avibactam enhances sulbactam activity against carbapenem-resistant Acinetobacter baumannii (CRAB) isolates. Antibiotics (Basel) 2021;10:577. - PMC - PubMed
    1. Poirel L, Sadek M, Nordmann P. Contribution of PER-type and NDM-type ss-lactamases to cefiderocol resistance in Acinetobacter baumannii. Antimicrob Agents Chemother 2021. AAC0087721. - PMC - PubMed

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