Eukaryotic evolution: Spatial proteomics sheds light on mitochondrial reduction
- PMID: 36473440
- DOI: 10.1016/j.cub.2022.10.039
Eukaryotic evolution: Spatial proteomics sheds light on mitochondrial reduction
Abstract
Multi-organelle spatial proteomics has revolutionized animal cell biology, but its use in protists has so far been limited. A new study delivers the first such proteome of a free-living protist, uncovering a previously overlooked function of highly reduced mitochondria.
Copyright © 2022 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
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Reduced mitochondria provide an essential function for the cytosolic methionine cycle.Curr Biol. 2022 Dec 5;32(23):5057-5068.e5. doi: 10.1016/j.cub.2022.10.028. Epub 2022 Nov 7. Curr Biol. 2022. PMID: 36347252 Free PMC article.
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