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. 2021 Mar 23;4(1):e000237.
doi: 10.1136/wjps-2020-000237. eCollection 2021.

Perioperative mortality in children in a tertiary teaching hospital in Nigeria: a prospective study

Ademola Olusegun Talabi  1 , Olugbenga Olalekan Ojo  1 , Olurotimi Idowu Aaron  2 , Oludayo Adedapo Sowande  1 , Folayemi Aramide Faponle  2 , Olusanya Adejuyigbe  1
Affiliations

Perioperative mortality in children in a tertiary teaching hospital in Nigeria: a prospective study

Ademola Olusegun Talabi et al. World J Pediatr Surg. .

Abstract

Background: Perioperative mortality is one of the tools that can help to assess the adequacy of healthcare delivery in a nation. This audit was conducted to determine the 24-hour, 7-day and 30-day perioperative mortality rates and the predictors of mortality in a pediatric surgical cohort.

Methods: This was a prospective study of children whose ages ranged from a few hours to 15 years and who were operated on between May 2019 and April 2020. The primary outcome was to determine the incidence of in-hospital perioperative mortality.

Results: A total of 530 procedures were done in 502 children. Their ages ranged from a few hours to 15 years with a median of 36 months. The 24-hour, 7-day and 30-day mortality rates were 113.2 per 10 000 procedures [95% confidence interval (CI) =40 to 210], 207.6 per 10 000 procedures (95% CI=110 to 320) and 320.8 per 10 000 procedures (95% CI=190 to 470), respectively. Congenital anomalies complicated by postoperative sepsis contributed to death in the majority of cases. The predictors of mortality were neonatal age group [adjusted odds ratio (AOR)=19.92, 95% CI=2.32 to 170.37, p=0.006], higher American Society of Anesthesiologists Physical Status III and above (AOR=21.6, 95% CI=3.05 to 152.91, p=0.002), emergency surgery (AOR=17.1, 95% CI=5.21 to 60.27, p=0.001), congenital anomalies (AOR=12.7, 95% CI=3.37 to 47.52, p=0.001), and multiple surgical procedures (AOR=9.7, 95% CI=2.79 to 33.54, p=0.001).

Conclusion: Perioperative mortality remains high in our institution.

Keywords: anesthetics; sudden infant death.

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Conflict of interest statement

Competing interests: None declared.

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