Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Dec 7;22(1):475.
doi: 10.1186/s12886-022-02715-1.

Perfluorocarbon liquid-assisted vitreo-dissection in eyes with firmly adherent posterior hyaloid

Affiliations

Perfluorocarbon liquid-assisted vitreo-dissection in eyes with firmly adherent posterior hyaloid

Ihab Abdel Aziz et al. BMC Ophthalmol. .

Abstract

Background: Induction of posterior vitreous detachment (PVD) is a critical step during pars plana vitrectomy. Multiple techniques and utilities have been proposed for assistance with this step with no consensus on the safest and most effective means, especially in eyes with firmly adherent posterior hyaloid. Viscodissection or the utilization of perfluorocarbon liquid (PFCL) can be used to dissect the posterior hyaloid and widely adherent epiretinal membranes.

Methods: A technique of PFCL dissection of the posterior hyaloid in eyes with abnormal adhesion of the posterior hyaloid. After core vitrectomy, breaking into the posterior hyaloid face is made via active aspiration and cutting or a sharp dissection. This is followed by active and slow injection of PFCL into the potential space between the posterior cortical vitreous and the neurosensory retina. A wave of PFCL propagates anteriorly causing "vitreo-dissection" of the peripheral cortical vitreous.

Results: The technique was effective and safe in 8 successive cases, 4 cases with vitreoretinal traction syndrome and 4 with diabetic tractional membranes.

Conclusion: The technique can be considered in cases with abnormal firmly adherent posterior hyaloid when induction of PVD proves difficult.

Keywords: PFCL; Pars Plana Vitrectomy; Perfluorocarbon liquid; Posterior vitreous detachment; Vitreo-dissection.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Vitreo-dissection technique using PFCL. Initial creation of a hole within the posterior hyaloid using active aspiration and cutting by the vitrectomy probe (A), followed by introduction of the PFCL cannula into the hole directed towards the potential space between the posterior cortical vitreous and the neurosensory retina (B), and injection of PFCL to form a bubble that propagates, elevating the posterior cortical vitreous away from the retina (C)

References

    1. Dhoot AS, Popovic MM, Nichani PAH, Eshtiaghi A, Mihalache A, Sayal AP, et al. Pars Plana Vitrectomy versus scleral buckle: a comprehensive meta-analysis of 15,947 eyes. Surv Ophthalmol. 2022;67(4):932–949. doi: 10.1016/j.survophthal.2021.12.005. - DOI - PubMed
    1. Berrocal MH, Acaba-Berrocal L. Early pars plana vitrectomy for proliferative diabetic retinopathy: update and review of current literature. Curr Opin Ophthalmol. 2021;32:203–208. doi: 10.1097/ICU.0000000000000760. - DOI - PubMed
    1. Santra M, Sharma M, Katoch D, Jain S, Saikia UN, Dogra MR, et al. Induction of posterior vitreous detachment (PVD) by non-enzymatic reagents targeting vitreous collagen liquefaction as well as vitreoretinal adhesion. Sci Rep. 2020;10:8250. doi: 10.1038/s41598-020-64931-3. - DOI - PMC - PubMed
    1. Tandias R, Lemire CA, Palvadi K, Arroyo JG. Posterior vitreous detachment status as a predictive factor for outcomes of vitrectomy for diabetic vitreous hemorrhage. Retina. 2022;42:1103–1110. doi: 10.1097/IAE.0000000000003453. - DOI - PubMed
    1. Ellabban AA, Barry R, Sallam AAB. Surgical induction of posterior vitreous detachment using combined sharp dissection and active aspiration. Acta Ophthalmol. 2016;94:e524–e525. doi: 10.1111/aos.12957. - DOI - PubMed

LinkOut - more resources