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. 2022 Dec 5;14(12):e32216.
doi: 10.7759/cureus.32216. eCollection 2022 Dec.

Assessment of Pre-existing Type 2 Diabetes Mellitus Prevalence and Risk Factors Among Colorectal Cancer Patients in King Abdulaziz Medical City, Jeddah

Abdulaziz A Saber  1 , Abdulrhman Alghamdi  1 , Albara J Raggam  1 , Loujen O Alamoudi  1 , Alhanoof Aljahdali  1 , Rayan M Bakheet  1 , Abdulrahman M Algethmi  1 , Muhammad A Khan  2 , Syed Faisal Zaidi  1   3
Affiliations

Assessment of Pre-existing Type 2 Diabetes Mellitus Prevalence and Risk Factors Among Colorectal Cancer Patients in King Abdulaziz Medical City, Jeddah

Abdulaziz A Saber et al. Cureus. .

Abstract

Background: Diabetes mellitus (DM) and cancer are recognized as non-communicable chronic disorders which are among the top ten causes of death globally. In Saudi Arabia, the prevalence of type 2 DM (T2DM) and colorectal cancer (CRC) is alarmingly high. Both T2DM and CRC share common risk factors. In this study, we aim to assess the prevalence of pre-existing T2DM among CRC Saudi patients.

Methods: In this cross-sectional study, data were collected from the medical records of 275 Saudi adult patients with CRC from 2009 to 2018 at King Abdulaziz Medical City, Jeddah (KAMC-J).

Results: Participants had a mean age of 57.0 years, standard deviation (SD) of 13.0, and were mostly males (60.00%) and Saudi (100.0%). Participants had a mean BMI of 26.42 (7.35) kg/m2. The prevalence of pre-existing T2DM in this study was 40.80%. 15.8% of participants were overweight and obese (BMI>30), respectively. The average age of diabetics and non-diabetics was 63.6 (10.64) and 52.73 (12.43), respectively. Diabetic patients are significantly older than non-diabetic patients (p<0.001). The average BMI for diabetics was 26.96 (7.26) kg/m2, whereas the average BMI for non-diabetics was 25.93 (7.48) kg/m2. No significant differences were found between the two groups.

Conclusion: This study provides new insight into the high prevalence of pre-existing T2DM in CRC patients in Saudi Arabia. In particular, the age of diagnosis of CRC in diabetic patients was significantly higher than in non-diabetics.

Keywords: body mass index (bmi); cigarette smoking; colorectal cancer; kingdom of saudi arabia (ksa); type 2 diabets mellitus.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Comparing the body mass index of diabetics and non-diabetics colorectal cancer patients
Figure 2
Figure 2. Comparing the age at diagnosis of colorectal cancer in diabetics and non-diabetics
Figure 3
Figure 3. Comparing different age groups of diabetics and non-diabetics with colorectal cancer
See this image and copyright information in PMC

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