Neuronal cultures playing Pong: First steps toward advanced screening and biological computing
- PMID: 36480938
- DOI: 10.1016/j.neuron.2022.11.010
Neuronal cultures playing Pong: First steps toward advanced screening and biological computing
Abstract
In this issue of Neuron, Kagan et al.1 implement learning-in-a-dish as an important step toward organoid intelligence. These systems may complement the study of molecular and cellular mechanisms of cognition and allow innovations in pharmacological and toxicological studies of neurodevelopmental or neurodegenerative disorders as well as advances in biological computing.
Copyright © 2022 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests T.H. is named inventor on a patent by Johns Hopkins University on the production of mini-brains (also called BrainSpheres), which is licensed to AxoSim, New Orleans, Louisiana, USA. T.H. and L.S. are consultants for AxoSim, New Orleans, and T.H. is also a consultant for AstraZeneca and American Type Culture Collection (ATCC) on advanced cell culture methods.
Comment on
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In vitro neurons learn and exhibit sentience when embodied in a simulated game-world.Neuron. 2022 Dec 7;110(23):3952-3969.e8. doi: 10.1016/j.neuron.2022.09.001. Epub 2022 Oct 12. Neuron. 2022. PMID: 36228614 Free PMC article.
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