A rare case of primary ovarian mesenchymal chondrosarcoma in pregnancy

Abstract

Mesenchymal chondrosarcoma is a rare tumor that is more common in young people; it is an uncommon type of chondrosarcoma with a poor prognosis. In two-thirds of cases, it affects the bone, especially the spine. However, parts of the body other than the skeletal system are occasionally involved. These rarer types have a worse prognosis, with a high likelihood of metastasis and death. Due to the possible misdiagnosis of mesenchymal chondrosarcoma, the integrated use of imaging, immunohistochemistry, and pathology can be helpful.

Keywords: Mesenchymal chondrosarcoma; Ovarian; Pregnancy.

Figure 1.

Magnetic resonance imaging, showing the fetus in the uterus on the right and the tumor in the left adnexa.

Figure 2.

Intraoperative image of the mass.

Figure 3.

Mesenchymal chondrosarcoma pathology with rhabdomyoblastic differentiation and without lymphovascular invasion. The mitotic rate was more than 18 per 10 high-power fields. There was a biphasic mesenchymal and chondrocyte pattern. The assay was performed by immunohistochemistry technique (×400).

Figure 4.

Post-chemotherapy (A) T2 axial, (B) apparent diffusion coefficient coronal, and (C) diffusion-weighted imaging coronal views on magnetic resonance imaging. An 86×36-mm mass in the left adnexa with central cystic changes suggested a hemorrhagic component, with no evidence of tumor recurrence.