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Case Reports
. 2022 Nov 22:9:1011206.
doi: 10.3389/fmed.2022.1011206. eCollection 2022.

Case report: Successful thromboprophylaxis with enoxaparin in a pregnant woman with internal jugular vein agenesis

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Case Reports

Case report: Successful thromboprophylaxis with enoxaparin in a pregnant woman with internal jugular vein agenesis

Pierpaolo Di Micco et al. Front Med (Lausanne). .

Abstract

Internal jugular agenesis is a vascular malformation that is often associated with a history of recurrent headache. Due to the resulting abnormalities in intracranial venous drainage, it may be complicated by neurological dysfunction, such as intracranial hypertension, intracranial micro-thromboses, and neurodegenerative diseases such as multiple sclerosis. The simultaneous presence of jugular vein agenesis and thrombosis is possible in cases of acute illness, hormonal treatment, pregnancy, hypomobility, or venous drainage abnormalities (VDA) (e.g., May-Thurner syndrome). In particular, the literature still lacks data on thromboprophylaxis in pregnant women with jugular vein agenesis. Here, we report a positive experience with prophylaxis using enoxaparin during pregnancy in a patient with internal jugular agenesis.

Keywords: enoxaparin; internal jugular agenesis; pregnancy; thromboprophylaxis; venous thromboembolism.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Collateral variceal venous circulation of the neck due to the presence of internal jugular agenesis.
Figure 2
Figure 2
Magnetic resonance imaging with evidence of internal jugular agenesis.

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References

    1. Mumtaz S, Singh M. Surgical review of the anatomical variations of the internal jugular vein: an update for head and neck surgeons. Ann R Coll Surg Engl. (2019) 101:2–6. 10.1308/rcsann.2018.0185 - DOI - PMC - PubMed
    1. Müller HR. Ultrasonic imaging of the internal jugular vein. J Neuroimaging. (1991) 1:74–8. 10.1111/jon19911274 - DOI - PubMed
    1. Lv X, Wu Z. Anatomic variations of internal jugular vein, inferior petrosal sinus and its confluence pattern: Implications in inferior petrosal sinus catheterization. Interv Neuroradiol. (2015) 21:769–73. 10.1177/1753425915590067 - DOI - PMC - PubMed
    1. Harbin MM, Lutsey PL. May-Thurner syndrome: History of understanding and need for defining population prevalence. J Thromb Haemost. (2020) 18:534–42. 10.1111/jth.14707 - DOI - PubMed
    1. Tufano A, López-Jiménez L, Bikdeli B, García-Bragado F, Mazzolai L, Amitrano M, et al. . Inferior vena cava agenesis in patients with lower limb deep vein thrombosis in the RIETE registry When and why to suspect. Int J Cardiol. (2020) 305:115–9. 10.1016/j.ijcard.2020.01.013 - DOI - PubMed

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