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Review
. 2022 Dec 1;30(4):495-500.
doi: 10.53854/liim-3004-3. eCollection 2022.

Clinical impact of COVID-19 on tuberculosis

Stefano Sanduzzi Zamparelli  1 , Mauro Mormile  2 , Alessandro Sanduzzi Zamparelli  2 , Amedeo Guarino  3 , Roberto Parrella  4 , Marialuisa Bocchino  2
Affiliations
Review

Clinical impact of COVID-19 on tuberculosis

Stefano Sanduzzi Zamparelli et al. Infez Med. .

Abstract

During COVID-19 pandemic, a lot of diseases suffered from a limited access to health care services, owing to the use of resources, both technical and financial, mainly directed towards such a dramatic outbreak. Among these, tuberculosis (TB) has been one of the most penalized, with a huge delay both in diagnosis and in start of treatment, with a consequential dramatic increase in morbidity and mortality. COVID-19 and tuberculosis share similar common pathogenetic pathways, and both diseases affect primarily the lungs. About the impact of TB on COVID-19 severity and mortality, data are unclear and literature reports are often conflicting. Certainly, considering the management of coinfected patients, there are pharmacokinetic interactions between several drugs used for the therapy of SARS-CoV-2 infection and the treatment of TB.

Keywords: BCG vaccination; Covid; Tuberculosis; epidemiology; immunology.

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Conflict of interest statement

Conflicts of interest The authors declare no conflict of interest.

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References

    1. WHO Coronavirus (COVID-19) Dashboard | WHO Coronavirus (COVID-19) Dashboard With Vaccination Data. n.d. [(accessed September 27, 2022)]. https://covid19.who.int/
    1. Global tuberculosis report 2021. n.d. [(accessed September 27, 2022)]. https://www.who.int/publications/i/item/9789240037021 .
    1. Formenti B, Gregori N, Crosato V, et al. The impact of COVID-19 on communicable and non-communicable diseases in Africa: a narrative review. Infez Med. 2022;30(1):30–40. - PMC - PubMed
    1. Khayat M, Fan H, Vali Y. COVID-19 promoting the development of active tuberculosis in a patient with latent tuberculosis infection: A case report. Respir Med Case Rep. 2021:32. doi: 10.1016/J.RMCR.2021.101344. - DOI - PMC - PubMed
    1. Ergönül Ö, Akyol M, Tanrıöver C, et al. National case fatality rates of the COVID-19 pandemic. Clin Microbiol Infect. 2021;27:118–124. doi: 10.1016/J.CMI.2020.09.024. - DOI - PMC - PubMed

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