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. 2022 Sep 26;2(1):e160.
doi: 10.1017/ash.2022.297. eCollection 2022.

Limited impact of a nudge comment in promoting de-escalation to first-generation cephalosporins in urinary tract infections

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Limited impact of a nudge comment in promoting de-escalation to first-generation cephalosporins in urinary tract infections

Martin T Brenneman et al. Antimicrob Steward Healthc Epidemiol. .

Abstract

In this study, we evaluated the impact of a microbiology nudge on de-escalation to first-generation cephalosporins in hospitalized patients with urinary tract infections secondary to Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis isolates with minimum inhibitory concentrations (MICs) ≤ 16 µg/mL. De-escalation to first generation-cephalosporins was uncommon at MICs = 4-16 µg/mL.

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