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Case Reports
. 2022 Dec 5;10(12):e6691.
doi: 10.1002/ccr3.6691. eCollection 2022 Dec.

Cerebral phaeohyphomycosis in liver transplant recipient: A case report

Kaleem Ullah  1 , Muhammad Asif Baig  1 , Abdul Wahab Dogar  1 , Shams Uddin  1 , Chaudhary Abdul Fatir  2 , Ali Asad  3 , Muhammad Junaid Tahir  2 , Ka Yiu Lee  4 , Khabab Abbasher Hussien Mohamed Ahmed  5 , Zohaib Yousaf  6
Affiliations
Case Reports

Cerebral phaeohyphomycosis in liver transplant recipient: A case report

Kaleem Ullah et al. Clin Case Rep. .

Abstract

Cerebral phaeohyphomycosis is a fungal brain infection with a high fatality rate. It is caused by dematiaceous fungi and is increasingly recognized as a cause of serious illness in both immunocompetent and immunocompromised patients. We report cerebral phaeohyphomycosis in a liver transplant recipient. He was treated with multiple surgeries and antifungals and made a complete recovery. This report highlights that early and aggressive surgical intervention and extended antifungal coverage can have a positive outcome even in immunocompromised patients. The fungal infection in immunocompromised patients should be considered and treated aggressively.

Keywords: Rhinocladiella mackenziei; brain; fungal infection; immunocompromised; pathogens.

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Conflict of interest statement

None.

Figures

FIGURE 1
FIGURE 1
(A and B): MRI showing ring‐enhancing lesion with peripheral edema in the left occipital region
FIGURE 2
FIGURE 2
Gram stain and hematoxylin and eosin (H&E) stain showing fungal septate hyphae with a diffuse mixed inflammatory infiltrate (10× and 40× magnification)
See this image and copyright information in PMC

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