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. 2023 Feb 6;13(2):255.
doi: 10.1158/2159-8290.CD-RW2022-213.

Myeloid-Derived Itaconate Suppresses Antitumor Immunity

No authors listed

Myeloid-Derived Itaconate Suppresses Antitumor Immunity

No authors listed. Cancer Discov. .

Abstract

Itaconate secreted by MDSCs suppresses CD8+ T-cell effector function and promotes tumor growth.

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