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Review
. 2023 Feb;47(2):220-235.
doi: 10.1002/jpen.2467. Epub 2022 Dec 29.

Medical nutrition therapy in patients receiving ECMO: Evidence-based guidance for clinical practice

Affiliations
Review

Medical nutrition therapy in patients receiving ECMO: Evidence-based guidance for clinical practice

Ellen Dresen et al. JPEN J Parenter Enteral Nutr. 2023 Feb.

Abstract

Patients receiving extracorporeal membrane oxygenation (ECMO) inherit substantial disease-associated metabolic, endocrinologic, and immunologic modifications. Along with the technical components of ECMO, the aforementioned alterations may affect patients' needs and feasibility of adequate macronutrient and micronutrient supply and intake. Thus, patients receiving ECMO are at increased risk for iatrogenic malnutrition and require targeted individual medical nutrition therapy (MNT). However, specific recommendations for MNT in patients receiving ECMO are limited and, with some exceptions, based on an evidence base encompassing general patients who are critically ill. Consequently, clinician decision-making for MNT in patients receiving ECMO is unguided, which may further increase nutrition risk, culminating in iatrogenic malnutrition and ultimately affecting patient outcomes. The purpose of this article is to provide educational background and highlight specific points for MNT in adult patients receiving ECMO, which might serve as evidence-based guidance to develop institutional standard operating procedures and nutrition protocols for daily clinical practice.

Keywords: critical illness; energy and nutrient supply; extracorporeal membrane oxygenation; medical nutrition therapy; monitoring; nutrition status/risk; practical guidance.

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References

REFERENCES

    1. Ramanathan K, Antognini D, Combes A, et al. Planning and provision of ECMO services for severe ARDS during the COVID-19 pandemic and other outbreaks of emerging infectious diseases. Lancet Respir Med. 2020;8(5):518-526.
    1. Yankah CA, Trimlett R, Sandoval E, et al. COVID-19 pulmonary failure and extracorporeal membrane oxygenation: first experience from three European Extracorporeal Membrane Oxygenation Centers. Thorac Cardiovasc Surg. 2021;69(3):259-262.
    1. Makdisi G, Wang I-W. Extra corporeal membrane oxygenation (ECMO) review of a lifesaving technology. J Thorac Dis. 2015;7(7):E166-176.
    1. Farías MM, Olivos C, Díaz R. Nutritional implications for the patient undergoing extracorporeal membrane oxygenation. Nutr Hosp. 2015;31(6):2346-2351.
    1. Kagan I, Singer P. Nutritional imbalances during extracorporeal life support. World Rev Nutr Diet. 2013;105:154-159.

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