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. 2023 Feb;70(2):e30089.
doi: 10.1002/pbc.30089. Epub 2022 Dec 10.

Sickle cell disease and social determinants of health: A scoping review

Hamda Khan  1 , Mathew Krull  2 , Jane S Hankins  1 , Winfred C Wang  1 , Jerlym S Porter  3
Affiliations

Sickle cell disease and social determinants of health: A scoping review

Hamda Khan et al. Pediatr Blood Cancer. 2023 Feb.

Abstract

Social determinants of health (SDoH) may impact outcomes in sickle cell disease (SCD). We conducted a comprehensive literature review of five electronic databases to elucidate the relationship between SDoH and SCD, and identify gaps in the literature. Our search yielded 59 articles, which we organized into five SDoH areas: Neighborhood and Built Environment, Health and Healthcare, Social and Community Context, Education, and Economic Stability. We found that social determinants, such as access to healthcare, were inconsistently evaluated. Improved recognition and understanding of SDoH should enhance the development of programs that directly address its detrimental effects on patients with SCD.

Keywords: environment; healthcare access; healthy literacy; quality of life; social determinants.

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Conflict of interest statement

CONFLICT OF INTEREST DISCLOSURES

JSH is a consultant for Global Blood Therapeutics and Forma Therapeutics.

JSP is a consultant for Forma Therapeutics.

Figures

Figure 1:
Figure 1:
PRISMA Flow Diagram for the Search of SCD and SDoH Literature
See this image and copyright information in PMC

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