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. 2023 Jan 9;41(2):519-531.
doi: 10.1016/j.vaccine.2022.11.072. Epub 2022 Dec 2.

Exploring key informants' perceptions of Covid-19 vaccine hesitancy in a disadvantaged urban community in Ireland: Emergence of a '4Cs' model

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Exploring key informants' perceptions of Covid-19 vaccine hesitancy in a disadvantaged urban community in Ireland: Emergence of a '4Cs' model

Carolyn Ingram et al. Vaccine. .

Abstract

Aim: The aim of this study was to explore key informants' views on and experiences with Covid-19 vaccine hesitancy in a Dublin community with a high concentration of economic and social disadvantage and to identify feasible, community-centred solutions for improving vaccination acceptance and uptake.

Methods: Qualitative, semi-structured interviews were carried out at a local community-centre and a central hair salon. Twelve key informants from the target community were selected based on their professional experience with vulnerable population groups: the unemployed, adults in recovery from addiction, the elderly, and Irish Travellers. Inductive thematic framework analysis was conducted to identify emergent themes and sub-themes.

Results: Drivers of vaccine hesitancy identified by key informants largely fell under the WHO '3Cs' model of hesitancy: lack of confidence in the vaccine and its providers, complacency towards the health risks of Covid-19, and inconvenient access conditions. Covid-19 Communications emerged as a fourth 'C' whereby unclear and negative messages, confusing public health measures, and unmet expectations of the vaccine's effectiveness exacerbated anti-authority sentiments and vaccine scepticism during the pandemic. Community-specific solutions involve the provision of accurate and accessible information, collaborating with community-based organizations to build trust in the vaccine through relationship building and ongoing dialogue, and ensuring acceptable access conditions.

Conclusions: The proposed Confidence, Complacency, Convenience, Covid-19 Communications ('4Cs') model provides a tool for considering vaccine hesitancy in disadvantaged urban communities reacting to the rapid development and distribution of a novel vaccine. The model and in-depth key informants' perspectives can be used to compliment equitable vaccination efforts currently underway by public health agencies and non-governmental organizations.

Keywords: Covid-19; Hesitancy drivers; Low-SES community; Qualitative; Socioeconomic disadvantage; Vaccine hesitancy.

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Comparison of Pobal HP Deprivation Index 2016 rankings and Covid-19 Vaccination Rates by national decile as of March 2022 in Dublin, Ireland. Note: The target community is a cluster of eight ‘Disadvantaged’ Small Areas (SA) within a Local Electoral Area (LEA) in the lowest decile for national vaccination rates. In Ireland, Covid-19 vaccination rates are not publicly available in spatial units smaller than LEAs.
Fig. 2
Fig. 2
Covid-19 vaccine topics included in the semi-structured interview guide. Note: key informants were asked about their own perceptions and experiences as well as those of the wider community.
Fig. 3
Fig. 3
4Cs’ Model of Covid-19 Vaccine Hesitancy in a disadvantaged urban community: inductive analysis results from key informant interviews, Dublin, Ireland 2021. *From the WHO SAGE Working Group 3Cs model of Vaccine Hesitancy . Covid-19 Communications emerged through inductive analysis as a separate theme driving hesitancy.
Fig. 4
Fig. 4
Drivers of vaccine resistance amongst adults in recovery from drug addiction as reported by community centre Guidance Counsellors (1) and (2): 19 November 2021, Dublin. *GP = General Practitioner. A&E = Accident and emergency department. HSE = Health Service Executive Ireland.

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