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. 2023 Jun;43(6):716-721.
doi: 10.1038/s41372-022-01576-2. Epub 2022 Dec 10.

Abdominal Near Infrared Spectroscopy can be reliably used to measure splanchnic oxygenation changes in preterm infants

R A Thomas #  1 , M-R Ballard #  1 , N Aladangady  2   3 , J Banerjee  4   5   6   7
Affiliations

Abdominal Near Infrared Spectroscopy can be reliably used to measure splanchnic oxygenation changes in preterm infants

R A Thomas et al. J Perinatol. 2023 Jun.

Abstract

Objective: Near-infrared spectroscopy (NIRS) allows assessment of regional tissue oxygen delivery and extraction. There are doubts regarding reliability of gut NIRS measurements. This study assesses reliability of NIRS for monitoring gut oxygenation.

Study design: Splanchnic tissue haemoglobin index (sTHI), tissue oxygenation index (sTOI) and fractional tissue oxygen extraction (sFTOE) changes during blood transfusion were measured using NIRS and compared to stable control infants. Infants were grouped into 3 chronological age groups: 1-7, 8-28 and ≥29 days of life.

Results: sTHI, sTOI significantly increased, and sFTOE reduced following blood transfusion in all age group infants (n = 59), with no changes seen in control infants (n = 12). Baseline characteristics including gestational age and feed volumes did not differ between groups.

Conclusion: Gut perfusion measured by NIRS improved in infants who received blood transfusion, a change not seen in the control group, thus suggesting NIRS is a reliable method to measure splanchnic tissue oxygenation.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1. Splanchnic NIRS measurements in transfused and control preterm infant groups.
Changes in sTOI (a), sFTOE (b) and sTHI (c) in transfused and control groups. **p < 0.001, *p < 0.01, NS not significant.
See this image and copyright information in PMC

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