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. 2022 Nov 26;19(23):15738.
doi: 10.3390/ijerph192315738.

Application of Percutaneous Needle Electrolysis Does Not Elicit Temperature Changes: An In Vitro Cadaveric Study

Sergio Borrella-Andrés  1 , Miguel Malo-Urriés  1 , Albert Pérez-Bellmunt  2   3 , José L Arias-Buría  4 , Jacobo Rodríguez-Sanz  2   3 , María Isabel Albarova-Corral  1 , Vanessa González-Rueda  2   3   5 , Gracia M Gallego-Sendarrubias  6 , César Fernández-de-Las-Peñas  4 , Carlos López-de-Celis  2   3   5
Affiliations

Application of Percutaneous Needle Electrolysis Does Not Elicit Temperature Changes: An In Vitro Cadaveric Study

Sergio Borrella-Andrés et al. Int J Environ Res Public Health. .

Abstract

Percutaneous needle electrolysis (PNE) consists of the ultrasound-guided application of a galvanic electrical current through a solid filament needle. One proposed therapeutic mechanism for this intervention is a potential thermal effect. The aim of this study was to investigate if the application of PNE induces changes in temperature in different cadaveric musculoskeletal tissues. A repeated measure experimental cadaveric study was designed with 10 cryopreserved knees (5 men, 5 women). Sterile stainless-steel needles of 40 mm length and 0.30 mm caliber were used in this study. An ultrasound-guided needling puncture was performed in the targeted tissue (patellar tendon, infra-patellar fat, and vastus medialis muscle). Additionally, the tip of the needle was placed next to the thermometer sensor at the minimum possible distance without direct contact with it. The temperature differences before and after different applications were measured. The applications were: three applications for 3 s of 3 mA of intensity (3:3:3) when the tendon was the targeted tissue, three applications for 3 s of 1.5 mA of intensity (1.5:3:3) when the fat or muscle was the targeted tissue, and 24 s of 1 mA of intensity (1:24:1) in all tissues. No statistically significant Group*Time interactions were found in any tissue (tendon: F = 0.571, p = 0.459, ŋ2 = 0.03; fat pad: F = 0.093; p = 0.764, ŋ2 = 0.01; muscle: F = 0.681; p = 0.420, ŋ2 = 0.04). Overall, no changes in temperature were observed between both applications in the tendon (3:3:3 vs. 1:24:1) and fat/muscle (1.5:3:3 vs. 1:24:1) tissues. The application of two different percutaneous needle electrolysis protocols did not produce appreciable thermal changes in the tendon, fat, and muscle tissues of human cadavers. The results from the current cadaver study support that a thermal effect should not be considered as a mechanism of clinical action regardless of the targeted human tissue when applying percutaneous needle electrolysis since no changes in temperature after its application were observed.

Keywords: EPI; cadaver; percutaneous needle electrolysis; temperature.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Percutaneous needle electrolysis on the vastus medialis on an anatomic sample.
Figure 2
Figure 2
Application of percutaneous needle electrolysis on the patellar tendon on an anatomic sample.
Figure 3
Figure 3
Application of percutaneous needle electrolysis on the infrapatellar fat pad of the knee on an anatomic sample.
See this image and copyright information in PMC

References

    1. Sánchez Ibañez J.M. Ph.D. Thesis. Atlantic International University; Honolulu, HI, USA: 2009. Clinical Course in the Treatment of Chronic Patellar Tendinopathy through Ultrasound Guided Percutaneous Electrolysis Intratissue (EPI®): Study of a Population Series of Cases in Sport.
    1. Abat F., Valles S.L., Gelber P.E., Polidori F., Jorda A., García-Herreros S., Monllau J.C., Sanchez-Ibáñez J.M. An Experimental Study of Muscular Injury Repair in a Mouse Model of Notexin-Induced Lesion with EPI® Technique. BMC Sports Sci. Med. Rehabil. 2015;7:7. doi: 10.1186/s13102-015-0002-0. - DOI - PMC - PubMed
    1. Mattiussi G., Moreno C. Treatment of Proximal Hamstring Tendinopathy Related Sciatic Nerve Entrapment: Presentation of an Ultrasound-Guided “Intratissue Percutaneous Electrolysis” Application. Muscles Ligaments Tendons J. 2016;6:248–252. doi: 10.32098/mltj.02.2016.13. - DOI - PMC - PubMed
    1. Margalef R., Valera-Garrido F., Minaya-Muñoz F., Bosque M., Ortiz N., Santafe M.M. Percutaneous Needle Electrolysis Reverses Neurographic Signs of Nerve Entrapment by Induced Fibrosis in Mice. Evid.-Based Complement. Altern. Med. 2020;2020:6615563. doi: 10.1155/2020/6615563. - DOI - PMC - PubMed
    1. Colmena C. New Technique in Tendon Sport Recovery. Percutaneous Electrolysis Intratissue (EPI®) Int. J. Phys. Med. R. habil. 2013;1:1000113. doi: 10.4172/2329-9096.1000113. - DOI

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