Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Dec 5;11(23):7226.
doi: 10.3390/jcm11237226.

Which Antibiotic for Urinary Tract Infections in Pregnancy? A Literature Review of International Guidelines

Mariela Corrales  1 , Elizabeth Corrales-Acosta  2 , Juan Guillermo Corrales-Riveros  3
Affiliations
Review

Which Antibiotic for Urinary Tract Infections in Pregnancy? A Literature Review of International Guidelines

Mariela Corrales et al. J Clin Med. .

Abstract

Urinary tract infection (UTI) is considered to be a major problem in pregnant women. It is also one of the most prevalent infections during pregnancy, being diagnosed in as many as 50-60% of all gestations. Therefore, UTI treatment during pregnancy is extremely important and management guidelines have been published worldwide to assist physicians in selecting the right antibiotic for each patient, taking into account the maternal and fetal safety profile. A review of the literature was carried out and all international guidelines giving recommendations about antibiotic treatments for pregnancy-related UTI were selected. The search came back with 13 guidelines from 4 different continents (8 from Europe, 3 from South America, 1 from North America and 1 from Oceania). Our review demonstrated concordance between guidelines with regard to several aspects in the antibiotic treatment of UTI during pregnancy and in the follow-up after treatment. Nonetheless, there are some areas of discordance, as in the case of antenatal screening for bacteriuria and the use of fluoroquinolones in lower or upper UTI. Given the current evidence that we have from international guidelines, they all agree on several key points about antibiotic use.

Keywords: UTI; asymptomatic; bacteriuria; cystitis; guideline; pregnancy; pyelonephritis; urinary tract infection; woman.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Flow chart of the literature review.
See this image and copyright information in PMC

References

    1. Waltzer W.C. The Urinary Tract in Pregnancy. J. Urol. 1981;125:271–276. doi: 10.1016/S0022-5347(17)55008-9. - DOI - PubMed
    1. Matuszkiewicz-Rowińska J., Małyszko J., Wieliczko M. Urinary tract infections in pregnancy: Old and new unresolved diagnostic and therapeutic problems. Arch. Med. Sci. 2015;11:67–77. doi: 10.5114/aoms.2013.39202. - DOI - PMC - PubMed
    1. Czajkowski K., Broś-Konopielko M., Teliga-Czajkowska J. Urinary tract infection in women. Prz. Menopauzalny Menopause Rev. 2021;20:40–47. doi: 10.5114/pm.2021.105382. - DOI - PMC - PubMed
    1. Baraka M.A., AlLehaibi L.H., AlSuwaidan H.N., Alsulaiman D., Islam A., Alotaibi B.S., Alboghdadly A., Homoud A.H., Al-Ghamdi F.H., Al Ghamdi M.S., et al. Patterns of infections and antimicrobial drugs’ prescribing among pregnant women in Saudi Arabia: A cross sectional study. J. Pharm. Policy Pract. 2021;14:9. doi: 10.1186/s40545-020-00292-6. - DOI - PMC - PubMed
    1. Glaser A.P., Schaeffer A.J. Urinary Tract Infection and Bacteriuria in Pregnancy. Urol. Clin. N. Am. 2015;42:547–560. doi: 10.1016/j.ucl.2015.05.004. - DOI - PubMed

LinkOut - more resources