HIV cure: an acceptability scientific agenda
- PMID: 36503877
- PMCID: PMC9757853
- DOI: 10.1097/COH.0000000000000771
HIV cure: an acceptability scientific agenda
Abstract
Purpose of review: Recent years have seen major investments into HIV cure research, seeking a permanent cure or remission. The purpose of this review is to consider how this important research agenda could be broadened to include issues of acceptability and appropriateness for different populations.
Recent findings: We discuss how the definitions of cure such as functional cure (remission) or complete cure (viral elimination) could be interpreted differently by various populations. We also discuss the different methods of cure and the importance of including Africa in cure research to ensure that emerging remedies could be trialled and utilized on the continent that bears the brunt of the AIDS pandemic.
Summary: We propose that the social science research of HIV cure acceptability should be done concurrently with the basic and clinical sciences, to ensure that cure methods consider stakeholder preferences.
Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc.
Conflict of interest statement
References
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- Bonney EY, Lamptey H, Aboagye JO, et al. Unwillingness of patients in Ghana to interrupt antiretroviral therapy for HIV cure research. J Virus Erad 2021; 7:100027. - PMC - PubMed
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One of the few quantitative survey studies in Africa on HIV patients’ perspective on cure trials and associated ATIs. They reported that patients have different perspectives compared with those in developed countries.
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