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Comment
. 2023 Mar;31(3):278.
doi: 10.1038/s41431-022-01237-0. Epub 2022 Dec 12.

Scientific refutation of ESHG statement on embryo selection

Laurent Christian Asker Melchior Tellier  1 , Nathan Robert Treff  2 , Stephen Dao Hui Hsu  2 , Louis Lello  2 , Erik Widen  2
Affiliations
Comment

Scientific refutation of ESHG statement on embryo selection

Laurent Christian Asker Melchior Tellier et al. Eur J Hum Genet. 2023 Mar.
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare the following interests: LT, NT, and SH are founders and shareholders of Genomic Prediction (GP). EW and LL are employees and shareholders of GP.

Comment in

  • Reply to Letter by Tellier et al., 'Scientific refutation of ESHG statement on embryo selection'.
    Forzano F, Antonova O, Clarke A, de Wert G, Hentze S, Jamshidi Y, Moreau Y, Perola M, Prokopenko I, Read A, Reymond A, Stefansdottir V, van El C, Genuardi M; Executive Committee of the European Society of Human Genetics; Public and Professional Policy Committee of the European Society of Human Genetics. Forzano F, et al. Eur J Hum Genet. 2023 Mar;31(3):279-281. doi: 10.1038/s41431-022-01241-4. Epub 2022 Dec 1. Eur J Hum Genet. 2023. PMID: 36450798 Free PMC article. No abstract available.

Comment on

  • The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice.
    Forzano F, Antonova O, Clarke A, de Wert G, Hentze S, Jamshidi Y, Moreau Y, Perola M, Prokopenko I, Read A, Reymond A, Stefansdottir V, van El C, Genuardi M; Executive Committee of the European Society of Human Genetics; Public and Professional Policy Committee of the European Society of Human Genetics. Forzano F, et al. Eur J Hum Genet. 2022 May;30(5):493-495. doi: 10.1038/s41431-021-01000-x. Epub 2021 Dec 17. Eur J Hum Genet. 2022. PMID: 34916614 Free PMC article.

References

    1. Forzano F, Antonova O, Clarke A, de Wert G, Hentze S, Jamshidi Y, et al. The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice. Eur J Hum Genet. 2022;30:493–5. doi: 10.1038/s41431-021-01000-x. - DOI - PMC - PubMed
    1. Lello L, Raben TG, Hsu SDH. Sibling validation of polygenic risk scores and complex trait prediction. Sci Rep. 2020;10:13190. doi: 10.1038/s41598-020-69927-7. - DOI - PMC - PubMed
    1. Turley P, Meyer MN, Wang N, Cesarini D, Hammonds E, Martin AR. et al. Problems with Using Polygenic Scores to Select Embryos. N Engl J Med. 2021;385:78–86. - PMC - PubMed
    1. Lencz T, Backenroth D, Granot-Hershkovitz E, Green A, Gettler K, Cho J, et al. Utility of polygenic embryo screening for disease depends on the selection strategy. eLife. 2021;10:e64716. doi: 10.7554/eLife.64716. - DOI - PMC - PubMed
    1. McGue M, Willoughby EA, Rustichini A, Johnson W, Iacono WG, Lee JJ. The contribution of cognitive and noncognitive skills to intergenerational social mobility. Psychological Sci. 2020;31:835–47. doi: 10.1177/0956797620924677. - DOI - PMC - PubMed