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Observational Study
. 2023 Jun;27(3):580-586.
doi: 10.1111/1744-9987.13960. Epub 2022 Dec 29.

Hemodialysis treatment for poisoning patients in the emergency department

Ugur Orhan  1 , Muge Gulen  2 , Salim Satar  2 , Selen Acehan  2 , Hakan Nazik  3 , Nurdan Unlu  4 , Mustafa Gediklioglu  2 , Cem Isikber  2 , Ahmet Sonmez  2 , Gökben Oral Sonmez  2
Affiliations
Observational Study

Hemodialysis treatment for poisoning patients in the emergency department

Ugur Orhan et al. Ther Apher Dial. 2023 Jun.

Abstract

Introduction: We aimed to evaluate the hemodialysis (HD) use in adult patients after acute poisoning in the emergency department.

Methods: The study was performed as a retrospective observational cohort study. We analyzed hospital electronic data system and patient files.

Results: A total of 55 patients were included in the study. Among the 10 toxins exposed, the most common were methanol and metformin. The most common indications for HD treatment were: 67.3% (n = 37) for toxin elimination, 20% (n = 11) for treatment-resistant metabolic acidosis, hemodynamic disorder. The most common complication (50.9%) in all patients was central nervous system depression. Ten patients died from ingestion of methanol, one of aluminum phosphide, and one of opioid-sympathomimetic-hallucinogen agents.

Conclusion: HD is the most commonly used extracorporeal treatment method in the treatment of poisoning patients. HD should be considered without any delay in treating poisoned patients if there is no response to conventional treatments.

Keywords: emergency; hemodialysis; methanol; poisoning.

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References

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