Safety evaluation of the food enzyme phytepsin from Cynara cardunculus L
- PMID: 36507101
- PMCID: PMC9727923
- DOI: 10.2903/j.efsa.2022.7681
Safety evaluation of the food enzyme phytepsin from Cynara cardunculus L
Abstract
The food enzyme phytepsin (EC 3.4.23.40) is extracted from the pistils of the cardoon Cynara cardunculus L. by ABIASA. It is intended to be used in milk processing for cheese production. As no concerns arose from the source of the food enzyme, from its manufacture, and based on the history of safe use and consumption, the Panel considered that toxicological data and the estimation of dietary exposure were not required. The Panel considered that allergic reactions to this phytepsin cannot be excluded in individuals allergic to this plant. However, the likelihood of allergic reactions to the phytepsin from C. cardunculus L. is expected not to exceed the likelihood of allergic reactions to cardoon. As the prevalence of allergic reactions to cardoon is low, also the likelihood of such reaction to occur to the food enzyme is low. Based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.
Keywords: Cynara cardunculus L.; EC 3.3.23.40; cardoon; flower; food enzyme; phytepsin; plant coagulant.
© 2022 Wiley‐VCH Verlag GmbH & Co. KgaA on behalf of the European Food Safety Authority.
References
-
- Cordeiro MC, Salomé M and Brodelius PE, 1994. Tissue‐specific expression of multiple forms of cyprosin (aspartic proteinase) in flowers of Cynara cardunculus . Physiologia Plantarum, 92, 645–653.
-
- EFSA (European Food Safety Authority) , 2009a. Guidance of EFSA prepared by the Scientific Panel of Food Contact Material, Enzymes, Flavourings and Processing Aids on the Submission of a Dossier on Food Enzymes. EFSA Journal 2009;7(8):1305, 26 pp. 10.2903/j.efsa.2009.1305 - DOI
-
- EFSA (European Food Safety Authority) , 2009b. Guidance of the Scientific Committee on transparency in the scientific aspects of risk assessments carried out by EFSA. Part 2: general principles. EFSA Journal 2009;7(5):1051, 22 pp. 10.2903/j.efsa.2009.1051 - DOI
LinkOut - more resources
Full Text Sources
Research Materials