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. 2022 Dec 27;328(24):2446-2447.
doi: 10.1001/jama.2022.21383.

Target Trial Emulation: A Framework for Causal Inference From Observational Data

Miguel A Hernán  1 , Wei Wang  2 , David E Leaf  3
Affiliations

Target Trial Emulation: A Framework for Causal Inference From Observational Data

Miguel A Hernán et al. JAMA. .
No abstract available

Plain language summary

This Guide to Statistics and Methods describes the use of target trial emulation to design an observational study so it preserves the advantages of a randomized clinical trial, points out the limitations of the method, and provides an example of its use.

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