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Review
. 2022 Sep 12;3(11):1980-1990.
doi: 10.34067/KID.0000792022. eCollection 2022 Nov 24.

Complications Associated with Continuous RRT

Samir C Gautam  1 , Jonathan Lim  1   2 , Bernard G Jaar  1   2   3   4
Affiliations
Review

Complications Associated with Continuous RRT

Samir C Gautam et al. Kidney360. .

Abstract

Continuous renal replacement therapy (CRRT) is a form of renal replacement therapy that is used in modern intensive care units (ICUs) to help manage acute kidney injury (AKI), end stage kidney disease (ESKD), poisonings, and some electrolyte disorders. CRRT has transformed the care of patients in the ICU over the past several decades. In this setting, it is important to recognize CRRT-associated complications but also up-to-date management of these complications. Some of these complications are minor, but others may be more significant and even life-threatening. Some CRRT complications may be related to dialysis factors and others to specific patient factors. Our overarching goal in this article is to review and discuss the most significant CRRT-related complications at the different stage of management of CRRT. With the advent of newer solutions, there have been newer complications as well.

Keywords: CRRT; ICU; acute kidney injury; acute kidney injury and ICU nephrology; bleeding; circuit; complications; dialysis; drugs; electrolytes; pneumothorax.

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Conflict of interest statement

S.C. Gautam reports ownership interest in BNGO, Criper, Invitae (stockholder), Sensonics, and Pacific Biosciences. B.G. Jaar reports honoraria from the American Board of Internal Medicine—Nephrology; patents or royalties from UpToDate; and an advisory or leadership role for the American Board of Internal Medicine, BMC Medicine, BMC Nephrology, the Clinical Journal of the American Society of Nephrology, and the National Kidney Foundation. The remaining author has nothing to disclose.

Figures

Figure 1.
Figure 1.
Continuous RRT (CRRT) cycle and complications.
Figure 2.
Figure 2.
Complications associated with CRRT.
Figure 3.
Figure 3.
Complications associated with CRRT.
Figure 3.
Figure 3.
Complications associated with CRRT.
Figure 4.
Figure 4.
Complications of catheter placement.
Figure 5.
Figure 5.
Complications of regional citrate anticoagulation.
See this image and copyright information in PMC

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