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Editorial
. 2022 Nov 24;3(11):1819-1822.
doi: 10.34067/KID.0005142022.

Minding the Gap Beyond Kidney Disease: Utility of the Anion Gap in Metabolic Syndrome

Affiliations
Editorial

Minding the Gap Beyond Kidney Disease: Utility of the Anion Gap in Metabolic Syndrome

Christina Tamargo et al. Kidney360. .
No abstract available

Keywords: CKD; acid-base equilibrium; acid/base and electrolyte disorders; acidosis; anion gap; metabolic syndrome; nonanion gap.

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Conflict of interest statement

C. Tamargo reports ownership interest in Amazon, Amedisys, AstraZeneca, Ayro, General Motors, Microsoft, Uber, and Vulcan. The remaining author has nothing to disclose.

Figures

Figure 1.
Figure 1.
Effects of metabolic acidosis in patients with CKD. Created with Biorender.com.

Comment on

References

    1. Hirode G, Wong RJ: Trends in the prevalence of metabolic syndrome in the United States, 2011–2016. JAMA 323: 2526–2528, 2020. 10.1001/jama.2020.4501 - DOI - PMC - PubMed
    1. Lambert DC, Abramowitz MK: Obesity and the risk of low bicarbonate: A cohort study. Kidney Med 3: 498–506, 2021. 10.1016/j.xkme.2021.02.006 - DOI - PMC - PubMed
    1. Lambert DC, Abramowitz MK: Obesity, anion accumulation, and anion gap metabolic acidosis: A cohort study. Kidney360 2: 1706–1715, 2021. 10.34067/KID.0003562021 - DOI - PMC - PubMed
    1. Kraut JA, Madias NE: Metabolic acidosis of CKD: An update. Am J Kidney Dis 67: 307–317, 2016. 10.1053/j.ajkd.2015.08.028 - DOI - PubMed
    1. Raphael KL, Zhang Y, Ying J, Greene T: Prevalence of and risk factors for reduced serum bicarbonate in chronic kidney disease. Nephrology (Carlton) 19: 648–654, 2014. 10.1111/nep.12315 - DOI - PubMed