Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Dec 9;10(12):e6596.
doi: 10.1002/ccr3.6596. eCollection 2022 Dec.

Anaphylaxis induced by intra-articular injection of chitosan: A case report and literature review

Affiliations
Case Reports

Anaphylaxis induced by intra-articular injection of chitosan: A case report and literature review

Shengxin Peng et al. Clin Case Rep. .

Abstract

Generally, we consider chitosan being a safe, nontoxic natural polymer with wide clinical applications. However, allergic reactions caused by chitosan have been reported on rare occasions. We report here a case of allergy and perform a literature review.

Keywords: anaphylaxis; chitosan; degenerative osteoarthropathy; intra‐articular injection.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interests.

Figures

FIGURE 1
FIGURE 1
Preparation of chitosan.
FIGURE 2
FIGURE 2
Properties and applications of chitosan
FIGURE 3
FIGURE 3
Flowchart of the literature review study.

References

    1. Patel S, Goyal A. Chitin and chitinase: role in pathogenicity, allergenicity and health. Int J Biol Macromol. 2017;97:331‐338. doi:10.1016/j.ijbiomac.2017.01.042 - DOI - PubMed
    1. Jayakumar R, Menon D, Manzoor K, Nair SV, Tamura H. Biomedical applications of chitin and chitosan based nanomaterials—a short review. Carbohydr Polym. 2010;82(2):227‐232. doi:10.1016/j.carbpol.2010.04.074 - DOI
    1. Singh BK, Sirohi R, Archana D, Jain A, Dutta PK. Porous chitosan scaffolds: a systematic study for choice of crosslinker and growth factor incorporation. 12.
    1. Mehta AS, Singh BK, Singh N, et al. Chitosan silk‐based three‐dimensional scaffolds containing gentamicin‐encapsulated calcium alginate beads for drug administration and blood compatibility. J Biomater Appl. 2015;29(9):1314‐1325. doi:10.1177/0885328214563148 - DOI - PubMed
    1. Singh J, Dutta PK. Preparation, circular dichroism induced helical conformation and optical property of chitosan acid salt complexes for biomedical applications. Int J Biol Macromol. 2009;45(4):384‐392. doi:10.1016/j.ijbiomac.2009.07.004 - DOI - PubMed

Publication types