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Case Reports
. 1979 Jan;22(1):71-6.
doi: 10.1002/art.1780220111.

Lymphocytes from synovial tissue of a boy with X-linked hypogammaglobulinemia and chronic polyarthritis

Case Reports

Lymphocytes from synovial tissue of a boy with X-linked hypogammaglobulinemia and chronic polyarthritis

T G Abrahamsen et al. Arthritis Rheum. 1979 Jan.

Abstract

Lymphocytes were eluted from synovial tissue of a boy with X-linked hypogammaglobulinemia and chronic polyarthritis. The cell suspension contained 53% lymphocytes and 28% peroxidase-positive, macrophagelike cells, No B lymphocytes, 83% T lymphocytes, and 10% Fc-receptor-bearing lymphocytes were detected. Lymphocyte transformation was induced by polyclonal mitogens (phytohemagglutinin and pokeweed mitogen) whereas no response to antigens (purified protein derivative and Candida albicans antigen) was obtained. The eluted cells displayed antibody-dependent cytotoxicity.

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