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. 2022 Dec 15;2022(60):125-134.
doi: 10.1093/jncimonographs/lgac022.

Through the Lens of Patient Partners: Challenges in Accrual of Older Adults to NCI Clinical Trials

Karlynn BrintzenhofeSzoc  1 , Beverly Canin  2 , Esmeralda Casas-Silva  3 , Andrea Denicoff  4 , Christa Braun-Inglis  5 , Izumi Okado  6 , Alexis Bakos  7
Affiliations

Through the Lens of Patient Partners: Challenges in Accrual of Older Adults to NCI Clinical Trials

Karlynn BrintzenhofeSzoc et al. J Natl Cancer Inst Monogr. .

Abstract

The workshop "Engaging Older Adults in Cancer Clinical Trials Conducted in the NCI Clinical Trials Network: Challenges and Opportunities" included a Patient Stakeholder Workgroup that explored the needs and concerns of older adults with cancer regarding clinical trials. To accomplish this, the workgroup conducted patient focus groups in which participants were interviewed, recorded conversations were analyzed and coded, and salient themes were identified. The focus groups identified general barriers to accrual such as complex consent forms, general communication, restrictive eligibility, nonreferrals, patient costs, cultural insensitivity, limited accessibility in community settings, and transportation issues. They also identified the influence of knowledgeable information presenters, improved care, family or caregiver support, and the desire to help others as drivers or reasons to participate in clinical trials. The workshop concluded that multi-level interventions could be used to increase the accrual of older adults to National Cancer Institute clinical trials as well as others.

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Figures

Figure 1.
Figure 1.
Original and modified barrier frameworks and conceptualization. Modifications to expand Context of Barriers Domain Framework developed by Unger et al. (29). Used with permission.
See this image and copyright information in PMC

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