Exploring the value of a global gene drive project registry

Riley I Taitingfong^#¹, Cynthia Triplett^#^{1

2}, Váleri N Vásquez^{3

4}, Ramya M Rajagopalan^{2

1}, Robyn Raban⁵, Aaron Roberts⁶, Gerard Terradas⁷, Bridget Baumgartner⁸, Claudia Emerson⁶, Fred Gould⁹, Fredros Okumu¹⁰, Cynthia E Schairer¹, Hervé C Bossin¹¹, Leah Buchman¹², Karl J Campbell¹³, Anna Clark¹⁴, Jason Delborne^{9

15}, Kevin Esvelt¹⁶, Joshua Fisher¹⁷, Robert M Friedman¹⁸, Gigi Gronvall^{19

20}, Nikos Gurfield²¹, Elizabeth Heitman²², Natalie Kofler²³, Todd Kuiken⁹, Jennifer Kuzma^{9

24}, Pablo Manrique-Saide²⁵, John M Marshall^{26

27}, Michael Montague²⁸, Amy C Morrison²⁹, Chris C Opesen³⁰, Ryan Phelan⁸, Antoinette Piaggio³¹, Hector Quemada³², Larisa Rudenko^{33

34}, Natéwindé Sawadogo³⁵, Robert Smith³⁶, Holly Tuten³⁷, Anika Ullah³⁸, Adam Vorsino¹⁷, Nikolai Windbichler³⁹, Omar S Akbari⁵, Kanya Long¹, James V Lavery^{40

41}, Sam Weiss Evans⁴², Karen Tountas⁴³, Cinnamon S Bloss^{44

45}

Affiliations

¹ Herbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, La Jolla, CA, USA.
² Center for Empathy and Technology, Institute for Empathy and Compassion, University of California, San Diego, La Jolla, CA, USA.
³ Energy and Resources Group, Rausser College of Natural Resources, University of California, Berkeley, Berkeley, CA, USA.
⁴ Department of Electrical Engineering and Computer Sciences, College of Engineering, University of California, Berkeley, Berkeley, CA, USA.
⁵ School of Biological Sciences, Department of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA, USA.
⁶ Institute on Ethics and Policy for Innovation, McMaster University, Hamilton, Ontario, Canada.
⁷ Department of Entomology, the Center for Infectious Disease Dynamics and the Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA, USA.
⁸ Revive & Restore, Sausalito, CA, USA.
⁹ Genetic Engineering and Society Center, North Carolina State University, Raleigh, NC, USA.
¹⁰ Environmental Health and Ecological Science Department, Ifakara Health Institute, Ifakara, Tanzania.
¹¹ Medical Entomology Laboratory, William A. Robinson Polynesian Research Center, Institut Louis Malardé, Papeete, Tahiti, French Polynesia.
¹² Department of Entomology, Texas A&M University, College Station, TX, USA.
¹³ Re:wild, Puerto Ayora, Galapagos Islands, Ecuador.
¹⁴ Department of Anatomy, University of Otago, Dunedin, Aotearoa New Zealand.
¹⁵ Department of Forestry and Environmental Resources, North Carolina State University, Raleigh, NC, USA.
¹⁶ Media Lab, Massachusetts Institute of Technology, Cambridge, MA, USA.
¹⁷ Pacific Islands Fish and Wildlife Office, United States Fish and Wildlife Service, Honolulu, HI, USA.
¹⁸ J. Craig Venter Institute, La Jolla, CA, USA.
¹⁹ Johns Hopkins Center for Health Security and Department of Environmental Health and Engineering, Baltimore, MD, USA.
²⁰ Bloomberg School of Public Health, Johns Hopkins, Baltimore, MD, USA.
²¹ Vector Control Program, Department of Environmental Health and Quality, County of San Diego, San Diego, CA, USA.
²² Program in Ethics in Science and Medicine, University of Texas Southwestern, Dallas, TX, USA.
²³ Scientific Citizenship Initiative, Harvard Medical School, Boston, MA, USA.
²⁴ School of Public and International Affairs, North Carolina State University, Raleigh, NC, USA.
²⁵ Laboratorio para el Control Biológico de Aedes aegypti, Unidad Colaborativa de Bioensayos Entomológicos, Campus de Ciencias Biológicas y Agropecuarias, Universidad Autónoma de Yucatán, Mérida, México.
²⁶ Divisions of Biostatistics & Epidemiology, School of Public Health, UC Berkeley, Berkeley, CA, USA.
²⁷ Innovative Genomics Institute, UC Berkeley, Berkeley, CA, USA.
²⁸ Center for Health Security, Johns Hopkins, Baltimore, MD, USA.
²⁹ Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, Davis, CA, USA.
³⁰ Department of Sociology and Anthropology, School of Social Sciences, Makerere University, Kampala, Uganda.
³¹ Animal and Plant Health Inspection Service, Wildlife Services, United States Department of Agriculture National Wildlife Research Center, Fort Collins, CO, USA.
³² Department of Biological Sciences, Western Michigan University, Kalamazoo, MI, USA.
³³ Massachusetts Institute of Technology, Cambridge, MA, USA.
³⁴ BioPolicy Solutions, LLC, Cambridge, MA, USA.
³⁵ University of Thomas Sankara, Ouagadougou, Burkina Faso.
³⁶ Science, Technology & Innovation Studies, School of Social & Political Science, The University of Edinburgh, Edinburgh, UK.
³⁷ Illinois Natural History Survey, Prairie Research Institute, University of Illinois at Urbana-Champaign, Champaign, IL, USA.
³⁸ David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
³⁹ Department of Life Sciences, Imperial College London, London, UK.
⁴⁰ Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
⁴¹ Center for Ethics, Emory University, Atlanta, GA, USA.
⁴² Program on Science, Technology & Society, Harvard University, Cambridge, MA, USA.
⁴³ GeneConvene Global Collaborative, Science Division, Foundation for the National Institutes of Health, North Bethesda, MD, USA.
⁴⁴ Herbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, La Jolla, CA, USA. cbloss@ucsd.edu.
⁴⁵ Center for Empathy and Technology, Institute for Empathy and Compassion, University of California, San Diego, La Jolla, CA, USA. cbloss@ucsd.edu.

^# Contributed equally.

PMID: 36522496
DOI: 10.1038/s41587-022-01591-w

Free article

Exploring the value of a global gene drive project registry

Riley I Taitingfong et al. Nat Biotechnol. 2023 Jan.

Free article

. 2023 Jan;41(1):9-13.

doi: 10.1038/s41587-022-01591-w.

Authors

Affiliations

¹ Herbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, La Jolla, CA, USA.
² Center for Empathy and Technology, Institute for Empathy and Compassion, University of California, San Diego, La Jolla, CA, USA.
³ Energy and Resources Group, Rausser College of Natural Resources, University of California, Berkeley, Berkeley, CA, USA.
⁴ Department of Electrical Engineering and Computer Sciences, College of Engineering, University of California, Berkeley, Berkeley, CA, USA.
⁵ School of Biological Sciences, Department of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA, USA.
⁶ Institute on Ethics and Policy for Innovation, McMaster University, Hamilton, Ontario, Canada.
⁷ Department of Entomology, the Center for Infectious Disease Dynamics and the Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA, USA.
⁸ Revive & Restore, Sausalito, CA, USA.
⁹ Genetic Engineering and Society Center, North Carolina State University, Raleigh, NC, USA.
¹⁰ Environmental Health and Ecological Science Department, Ifakara Health Institute, Ifakara, Tanzania.
¹¹ Medical Entomology Laboratory, William A. Robinson Polynesian Research Center, Institut Louis Malardé, Papeete, Tahiti, French Polynesia.
¹² Department of Entomology, Texas A&M University, College Station, TX, USA.
¹³ Re:wild, Puerto Ayora, Galapagos Islands, Ecuador.
¹⁴ Department of Anatomy, University of Otago, Dunedin, Aotearoa New Zealand.
¹⁵ Department of Forestry and Environmental Resources, North Carolina State University, Raleigh, NC, USA.
¹⁶ Media Lab, Massachusetts Institute of Technology, Cambridge, MA, USA.
¹⁷ Pacific Islands Fish and Wildlife Office, United States Fish and Wildlife Service, Honolulu, HI, USA.
¹⁸ J. Craig Venter Institute, La Jolla, CA, USA.
¹⁹ Johns Hopkins Center for Health Security and Department of Environmental Health and Engineering, Baltimore, MD, USA.
²⁰ Bloomberg School of Public Health, Johns Hopkins, Baltimore, MD, USA.
²¹ Vector Control Program, Department of Environmental Health and Quality, County of San Diego, San Diego, CA, USA.
²² Program in Ethics in Science and Medicine, University of Texas Southwestern, Dallas, TX, USA.
²³ Scientific Citizenship Initiative, Harvard Medical School, Boston, MA, USA.
²⁴ School of Public and International Affairs, North Carolina State University, Raleigh, NC, USA.
²⁵ Laboratorio para el Control Biológico de Aedes aegypti, Unidad Colaborativa de Bioensayos Entomológicos, Campus de Ciencias Biológicas y Agropecuarias, Universidad Autónoma de Yucatán, Mérida, México.
²⁶ Divisions of Biostatistics & Epidemiology, School of Public Health, UC Berkeley, Berkeley, CA, USA.
²⁷ Innovative Genomics Institute, UC Berkeley, Berkeley, CA, USA.
²⁸ Center for Health Security, Johns Hopkins, Baltimore, MD, USA.
²⁹ Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, Davis, CA, USA.
³⁰ Department of Sociology and Anthropology, School of Social Sciences, Makerere University, Kampala, Uganda.
³¹ Animal and Plant Health Inspection Service, Wildlife Services, United States Department of Agriculture National Wildlife Research Center, Fort Collins, CO, USA.
³² Department of Biological Sciences, Western Michigan University, Kalamazoo, MI, USA.
³³ Massachusetts Institute of Technology, Cambridge, MA, USA.
³⁴ BioPolicy Solutions, LLC, Cambridge, MA, USA.
³⁵ University of Thomas Sankara, Ouagadougou, Burkina Faso.
³⁶ Science, Technology & Innovation Studies, School of Social & Political Science, The University of Edinburgh, Edinburgh, UK.
³⁷ Illinois Natural History Survey, Prairie Research Institute, University of Illinois at Urbana-Champaign, Champaign, IL, USA.
³⁸ David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
³⁹ Department of Life Sciences, Imperial College London, London, UK.
⁴⁰ Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
⁴¹ Center for Ethics, Emory University, Atlanta, GA, USA.
⁴² Program on Science, Technology & Society, Harvard University, Cambridge, MA, USA.
⁴³ GeneConvene Global Collaborative, Science Division, Foundation for the National Institutes of Health, North Bethesda, MD, USA.
⁴⁴ Herbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, La Jolla, CA, USA. cbloss@ucsd.edu.
⁴⁵ Center for Empathy and Technology, Institute for Empathy and Compassion, University of California, San Diego, La Jolla, CA, USA. cbloss@ucsd.edu.

^# Contributed equally.

PMID: 36522496
DOI: 10.1038/s41587-022-01591-w

No abstract available

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References

1. National Academies of Sciences, Engineering, and Medicine. Gene Drives on the Horizon: Advancing Science, Navigating Uncertainty, and Aligning Research with Public Values (National Academies Press, 2016).
1. Warmbrod, K. L., Kobokovich, A. L., West, R., Gronvall, G. K. & Montague, M. Health Secur. 20, 43–49 (2022). - DOI
1. Kofler, N. et al. Science 362, 527–529 (2018). - DOI
1. Rubinstein, W. S. et al. Nucleic Acids Res. 41, D925–D935 (2013). - DOI
1. World Health Organization. Human Genome Editing (HGE) Registry https://www.who.int/groups/expert-advisory-committee-on-developing-globa... (accessed 9 November 2021).

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Exploring the value of a global gene drive project registry

Affiliations

Exploring the value of a global gene drive project registry

Authors

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