Anti-Diarrheal Activities of Hydromethanolic Crude Extract and Solvent Fractions of Acacia seyal (Fabaceae) Roots in Mice [Response to Letter]

Affiliations

Comment

Assefa Kebad Mengesha et al. Clin Pharmacol. 2022.

. 2022 Dec 8:14:113-114.

doi: 10.2147/CPAA.S400000. eCollection 2022.

¹ Department of Pharmacology, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

No abstract available

Conflict of interest statement

The authors disclose no conflicts of interest in this communication.

A Response to Article "Anti-Diarrheal Activity of Hydromethanolic Crude Extract and Solvent Fractions of Acacia Seyal (Fabaceae) Roots in Mice" [Letter].
Panjaitan NSD, Fitriana F, Handayani S. Panjaitan NSD, et al. Clin Pharmacol. 2022 Nov 29;14:111-112. doi: 10.2147/CPAA.S398217. eCollection 2022. Clin Pharmacol. 2022. PMID: 36471876 Free PMC article. No abstract available.

1. Kinuthia DG, Muriithi AW, Mwangi PW. Freeze dried extracts of Bidens biternata (Lour.) Merr. and Sheriff. show significant antidiarrheal activity in in-vivo models of diarrhea. J Ethnopharmacol. 2016;193:416–422. doi:10.1016/j.jep.2016.09.041 - DOI - PubMed
1. Tunaru S, Althoff TF, Nüsing RM, Diener M, Offermanns S. Castor oil induces laxation and uterus contraction via ricinoleic acid activating prostaglandin EP3 receptors. Proc Natl Acad Sci. 2012;109(23):9179–9184. doi:10.1073/pnas.1201627109 - DOI - PMC - PubMed
1. Wu GY. Clinical Gastroenterology. Springer; 2010.
1. Binder HJ. The pathophysiology of diarrhea. Hosp Pract. 1984;19(10):107–118. doi:10.1080/21548331.1984.11702924 - DOI - PubMed
1. Shah S. Evaluation of diarrhea: the challenge continues! Part-I. Ind J Med Sci. 2004;58(2):75–78. - PubMed