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. 2023 Jan 9;41(1):9-11.
doi: 10.1016/j.ccell.2022.11.008. Epub 2022 Dec 15.

T cell-eosinophil crosstalk-A new road for effective immune checkpoint blockade in breast cancer?

Sharon Grisaru-Tal  1 , Ariel Munitz  2
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T cell-eosinophil crosstalk-A new road for effective immune checkpoint blockade in breast cancer?

Sharon Grisaru-Tal et al. Cancer Cell. .
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Abstract

Immune checkpoint blockade (ICB) has revolutionized the landscape of cancer treatment. Nevertheless, most cancer patients still do not respond to ICB. In this issue of Cancer Cell, Blomberg et al. illustrate a critical cooperation between T cells and eosinophils, which jointly enhance effectiveness of ICB in breast cancer.

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