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Review
. 2023 Mar;53(2):104637.
doi: 10.1016/j.idnow.2022.12.002. Epub 2022 Dec 13.

Spread of viruses, which measures are the most apt to control COVID-19?

Y Tandjaoui-Lambiotte  1 , A Lomont  2 , P Moenne-Locoz  2 , D Seytre  2 , J R Zahar  3
Affiliations
Review

Spread of viruses, which measures are the most apt to control COVID-19?

Y Tandjaoui-Lambiotte et al. Infect Dis Now. 2023 Mar.

Abstract

The persistent debate about the modes of transmission of SARS-CoV2 and preventive measures has illustrated the limits of our knowledge regarding the measures to be implemented in the face of viral risk. Past and present (pandemic-related) scientific data underline the complexity of the phenomenon and its variability over time. Several factors contribute to the risk of transmission, starting with incidence in the general population (i.e., colonization pressure) and herd immunity. Other major factors include intensity of symptoms, interactions with the reservoir (proximity and duration of contact), the specific characteristics of the virus(es) involved, and a number of unpredictable elements (humidity, temperature, ventilation…). In this review, we will emphasize the difficulty of "standardizing" the situations that might explain the discrepancies found in the literature. We will show that the airborne route remains the main mode of transmission. Regarding preventive measures of prevention, while vaccination remains the cornerstone of the fight against viral outbreaks, we will remind the reader that wearing a mask is the main barrier measure and that the choice of type of mask depends on the risk situations. Finally, we believe that the recent pandemic should induce us in the future to modify our recommendations by adapting our measures in hospitals, not to the pathogen concerned, which is currently the case, but rather to the type of at-risk situation.

Keywords: Airborne transmission; COVID-19; Hand hygiene; Mask; Preventive measures.

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References

    1. Rule A.M., Apau O., Ahrenholz S.H., Brueck S.E., Lindsley W.G., de Perio M.A., et al. Healthcare personnel exposure in an emergency department during influenza season. PLoS One. 2018;13(8):e0203223. - PMC - PubMed
    1. Yan J., Grantham M., Pantelic J., Bueno de Mesquita P.J., Albert B., Liu F., et al. Infectious virus in exhaled breath of symptomatic seasonal influenza cases from a college community. Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):1081–1086. - PMC - PubMed
    1. Tran K., Cimon K., Severn M., Pessoa-Silva C.L., Conly J. Aerosol generating procedures and risk of transmission of acute respiratory infections to healthcare workers: a systematic review. PLoS One. 2012;7(4):e35797. - PMC - PubMed
    1. Thomas R.E. Do we have enough evidence how seasonal influenza is transmitted and can be prevented in hospitals to implement a comprehensive policy? Vaccine. 2016 Jun 8;34(27):3014–3021. - PMC - PubMed
    1. Salgado C.D., Farr B.M., Hall K.K., Hayden F.G. Influenza in the acute hospital setting. Lancet Infect Dis. 2002 Mar;2(3):145–155. - PubMed