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Case Reports
. 2022 Dec 12:10:2050313X221142236.
doi: 10.1177/2050313X221142236. eCollection 2022.

Rapid neurodevelopmental recovery after ART initiation in an infant with HIV encephalopathy

Denise Quincardete  1 , Muhammad Sidat  2 , Gurpreet Seehra  3 , Kiran Mitha  3 , Uneisse Cassia  2 , Alfeu Passanduca  2 , Stella Langa  1 , Sónia Martins  2 , Beatriz Elias  1 , W Chris Buck  2   3
Affiliations
Case Reports

Rapid neurodevelopmental recovery after ART initiation in an infant with HIV encephalopathy

Denise Quincardete et al. SAGE Open Med Case Rep. .

Abstract

While there is ample evidence that antiretroviral therapy (ART) can improve cognitive outcomes in older children living with HIV, encephalopathy in infants has historically been considered an advanced disease presentation with less likelihood of neurodevelopmental recovery on treatment. More recent studies suggest that timely ART can halt encephalopathic disease progression and even lead to symptom resolution. Here we present a case of an HIV-positive infant diagnosed with encephalopathy who experienced impressive and rapid improvement with a multi-disciplinary care approach that included physical and occupational therapy and ART.

Keywords: ART; HIV; encephalopathy; infant.

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Conflict of interest statement

The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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