Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Feb:32:74-76.
doi: 10.1016/j.jdcr.2022.12.001. Epub 2022 Dec 13.

Indolent cutaneous lymphoma with gamma/delta expression after COVID-19 vaccination

Affiliations

Indolent cutaneous lymphoma with gamma/delta expression after COVID-19 vaccination

Catherine Grace Hobayan et al. JAAD Case Rep. 2023 Feb.
No abstract available

Keywords: COVID-19 vaccine; cutaneous lymphoma; gamma/delta T-cell lymphoma; general dermatology; injection site reaction; medical dermatology; oncology; pathology; viral vector vaccine.

PubMed Disclaimer

Conflict of interest statement

None disclosed.

Figures

Fig 1
Fig 1
A, Ulcerated plaque with surrounding erythema at the vaccine site on the left upper arm at initial presentation. B, Subtle pink patch on right upper arm 5 months following initial presentation. C, Well-healed scar on left upper arm with no palpable masses or lymphadenopathy 5 months following initial presentation.
Fig 2
Fig 2
A, Histopathology reveals ulceration with a diffuse lymphoid infiltrate that replaces the dermis and subcutaneous fat. B, The lymphocytes are characterized by atypia and associated with numerous “bean bag” cells. C, The lymphocytes are negative for T-cell receptor (TCR) BetaF1 and positive for TCR Delta. (A, H&E original magnification × 5; B, H&E original magnification × 200; and C and D, original magnification × 200).

Similar articles

Cited by

References

    1. Kreher M.A., Ahn J., Werbel T., Motaparthi K. Subcutaneous panniculitis-like T-cell lymphoma after COVID-19 vaccination. JAAD Case Rep. 2022;28:18–20. - PMC - PubMed
    1. Guitart J., Weisenburger D.D., Subtil A., et al. Cutaneous γδ T-cell lymphomas: a spectrum of presentations with overlap with other cytotoxic lymphomas. Am J Surg Pathol. 2012;36:1656–1665. - PubMed
    1. Alberti-Violetti S., Maronese C.A., Benegoni L., Merlo V., Berti E. Primary cutaneous gamma-delta T cell lymphomas: a case series and overview of the literature. Dermatopathology. 2021;8:515–524. - PMC - PubMed
    1. Khallaayoune M., Grange F., Condamina M., Szablewski V., Guillot B., Dereure O. Primary cutaneous gamma-delta T-cell lymphoma: not an aggressive disease in all cases. Acta Derm Venereol. 2020;100 - PMC - PubMed
    1. von Dücker L., Fleischer M., Stutz N., et al. Primary cutaneous gamma-delta T-cell lymphoma with long-term indolent clinical course initially mimicking lupus eruthematosus profundus. Front Oncol. 2020;10:133. - PMC - PubMed