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. 1987;236(5):257-9.
doi: 10.1007/BF00380949.

Blood-cerebrospinal fluid barrier in schizophrenic patients

K Bauer  1 , J Kornhuber
Affiliations

Blood-cerebrospinal fluid barrier in schizophrenic patients

K Bauer et al. Eur Arch Psychiatry Neurol Sci. 1987.

Abstract

A total of 15 young white male patients newly diagnosed as schizophrenic (DMS III) were examined for signs of blood-cerebrospinal fluid (CSF) barrier alteration and CNS IgG synthesis. Of the 15 patients, 8 exhibited signs of increased blood-CSF barrier permeability. There was a high correlation between the ratio for CSF/serum albumin concentration and the CSF total protein concentration. Local IgG synthesis in the CNS was not detected in any of the patients.

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