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. 2022 Dec 1:13:1018176.
doi: 10.3389/fpsyg.2022.1018176. eCollection 2022.

Psychometric properties and construct validity of the Parkinson's Disease-Cognitive Rating Scale (PD-CRS) in Colombia

Hugo Juan Camilo Clavijo-Moran  1 , Daniela Álvarez-García  2   3 , Gabriel D Pinilla-Monsalve  4 , Beatriz Muñoz-Ospina  5 , Jorge Orozco  6
Affiliations

Psychometric properties and construct validity of the Parkinson's Disease-Cognitive Rating Scale (PD-CRS) in Colombia

Hugo Juan Camilo Clavijo-Moran et al. Front Psychol. .

Abstract

Background: Cognitive impairment is frequent among people living with Parkinson's disease: up to 40% of patients exhibit symptoms of mild cognitive impairment and 25% meet the criteria for dementia. Parkinson's Disease Cognitive Rating Scale (PD-CRS) is one of the recommended scales by the Movement Disorders Society Task Force for level 1 screening of dementia. However, its psychometric properties have not been studied in the Colombian population.

Methods: A cross-sectional study was conducted on 100 patients with Parkinson's disease diagnosed by a movement disorders neurologist. Patients were evaluated with PD-CRS and MoCA. Principal component analysis was conducted, and then confirmatory factor analysis was implemented through the maximum-likelihood method. Internal consistency was evaluated using Cronbach α. Convergent and divergent validity were also calculated and concurrent validity with the MoCA was assessed.

Results: 62% were males. Their median age was 68 years (IQR 57-74) and the median disease duration was 4 years (IQR 2-9). 77% were classified in early stages (Hoehn and Yahr stage ≤ 2), while the MDS-UPDRS part III score was 25 (IQR 15.5-38). In the principal component factor analysis, the pattern matrix unveiled a mnesic and a non-mnesic domain. Confirmatory factor analysis showed similar explanatory capacity (λ ≥ 0.50) for items other than naming (λ = 0.34). Cronbach's α for the full 9-items instrument was 0.74. MoCA and PD-CRS total scores were correlated (ρ = 0.71, p = 0.000). Assuming a cut-off score of 62 points, there is an agreement of 89% with the definition of dementia by MoCA for Colombia (κ = 0.59; p = 0.000).

Conclusion: PD-CRS has acceptable psychometric properties for the Colombian population and has significant correlation and agreement with a validated scale (MoCA).

Keywords: PD-CRS; Parkinson’s disease; Parkinson’s disease dementia; cognitive impairment; psychometric.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Total PD-CRS per MDS motor subtype and stage of disease according to the Hoehn and Yahr classification.
Figure 2
Figure 2
Figure 3
Figure 3
See this image and copyright information in PMC

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