Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Nov 17:84:104891.
doi: 10.1016/j.amsu.2022.104891. eCollection 2022 Dec.

Clinical profile and risk factors of cerebral venous sinus thrombosis (CVST) in Sudan: A multicenter cross-sectional study

Etedal Ahmed A Ibrahim  1 , Rofiedah Eisa Hassan Mohamed  2 , Khabab Abbasher Hussien Mohamed Ahmed  3 , Mazin S Haroun  3 , Yassin Abdelrahim Abdalla  4 , Mohammed Eltahier Abdalla Omer  5 , Mohammed Mahmmoud Fadelallah Eljack  6
Affiliations

Clinical profile and risk factors of cerebral venous sinus thrombosis (CVST) in Sudan: A multicenter cross-sectional study

Etedal Ahmed A Ibrahim et al. Ann Med Surg (Lond). .

Abstract

Background: Cerebral venous sinus thrombosis (CVST) is a relatively uncommon cause of stroke that mainly affects young ladies, with a wide spectrum of symptoms severity, and prognosis. In this study, we aim to study the clinical profile and Risk Factors of CVST among Sudanese patients in Khartoum state hospitals.

Methods: This was a multi-center cross-sectional hospital-based study that covered 37 participants in three major hospitals in Khartoum, with radiologically confirmed Cerebral Venous Sinus Thrombosis (CVST).

Results: About 37 patients were included in this study. The median age was 35 years; the range was 52 years, with a minimum age of 23 years and a maximum of 75 years. The commonest presenting feature was headache (n = 35; 94.6%), followed by blurring of vision (n = 25; 67.6%), while seizures is a presenting symptom in nearly half of the patients (n = 17; 45.9%), on examination papilledema was present in 83.8%. In this study 13.8% were pregnant, 31.0% were postpartum and OCPS users account for 27%. Regarding the involved sinus; Sagittal Venous Sinus and the transverse sinus were the most affected sinuses. Regarding treatment options: "low molecular weight heparin followed with warfarin" was found in 81.1%, followed by heparin in only 10.8%, while the new agents NOACs comprised only 8.1%.

Conclusion: Cerebral Venous Sinus Thrombosis is mainly a disease of child-bearing women, although significant proportions of men were affected. Cerebral Venous Sinus Thrombosis presents in a wide variety of signs and symptoms.

Keywords: CVST; Cerebral venous sinus thrombosis; Clinical profile; Neurology; Risk factor; Sudan.

PubMed Disclaimer

Conflict of interest statement

Authors report no conflict of interest.

Figures

Fig. 1
Fig. 1
Showed the distribution of the patients according to their risk factors for Cerebral Venous Sinus Thrombosis (CVST).
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Luo Y., Tian X., Wang X. vol. 10. 2018. (Diagnosis and Treatment of Cerebral Venous Thrombosis : A Review). (January) - PMC - PubMed
    1. Stam J. vols. 1791–8. 2005. (Thrombosis of the Cerebral Veins and Sinuses). - PubMed
    1. Capecchi M., Abbattista M., Martinelli I. Cerebral venous sinus thrombosis. J. Thromb. Haemostasis. 2018;16(10):1918–1931. - PubMed
    1. Kimber J. vols. 137–42. 2002. (QJM Cerebral Venous Sinus Thrombosis). - PubMed
    1. Agnelli G., Verso M. Epidemiology of cerebral vein and sinus thrombosis. Front Neurol Neurosci. 2008;23:16–22. - PubMed