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. 2022 Dec 10:2022:3422578.
doi: 10.1155/2022/3422578. eCollection 2022.

Verbal Reasoning Impairment in Parkinson's Disease

Antonina Luca  1 , Giulia Donzuso  1 , Concetta D'Agate  1 , Claudio Terravecchia  1 , Calogero Cicero Edoardo  1 , Giovanni Mostile  1   2 , Giorgia Sciacca  1 , Alessandra Nicoletti  1 , Mario Zappia  1
Affiliations

Verbal Reasoning Impairment in Parkinson's Disease

Antonina Luca et al. Behav Neurol. .

Abstract

Background: The aim of this study was to assess verbal reasoning (VR) functioning in patients with Parkinson's disease (PD) and healthy controls (HCs).

Methods: The non-demented PD patients and HCs matched by age and global cognition were enrolled in this study. VR was assessed with the verbal reasoning test (VRT), total score, and subsets.

Results: Eighty-seven PD patients (51 men; mean age 63.8 ± 7.9 years) and 87 HCs (46 men; mean age 63.7 ± 8.0 years) were enrolled. At univariate analysis, PD patients presented a significantly lower score in the VRT subset classification (12.3 ± 2.1) than HCs (12.9 ± 1.7) with an odds ratio (OR) of 0.8 (95% confidence interval [CI] 0.70-0.98; p = 0.003). The strength of association was also confirmed at multivariate analysis (OR = 0.8, 95% CI 0.70-0.98; p = 0.003). Moreover, in PD patients, a statistically significant positive correlation was found between VRT-classification and MoCA scores (r = 0.330; p = 0.002).

Conclusions: PD patients presented lower VR performance than HCs.

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Conflict of interest statement

The author(s) declare(s) that they have no conflicts of interest.

Figures

Figure 1
Figure 1
Pearson's correlation between MoCA scores and VRT-classification in patients with Parkinson's disease.
See this image and copyright information in PMC

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