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Editorial
. 2022 Sep;17(3):602-606.
doi: 10.26574/maedica.2022.17.3.602.

Mastitis and Risk of Breast Cancer: a Case Control-Retrospective Study and Mini-Review

Anastasia Bothou  1   2   3 , Stefanos Zervoudis  4 , Panagiota Pappou  1 , Georgios Tsatsaris  3 , Aggeliki Gerede  3 , Georgios Dragoutsos  3 , Anna Chalkidou  3 , Konstantinos Nikolettos  3 , Panagiotis Tsikouras  3
Affiliations
Editorial

Mastitis and Risk of Breast Cancer: a Case Control-Retrospective Study and Mini-Review

Anastasia Bothou et al. Maedica (Bucur). 2022 Sep.

Abstract

Objective: To investigate a possible association between mastitis and breast cancer risk in a cohort of Greek women. Material and methods:A series of 343 women who visited two breast clinics in Greece and delivered live neonates were studied in our case-control retrospective study. The case group comprised women with breast cancer and the control group women without breast cancer. All participants were subjected to a clinical examination with breast ultrasound and those aged over 40 years underwent digital bilateral mammography. Results:The χ2 (chi-square) test was the statistical tool used by us. We noted a statistically significant relationship between mastitis and risk for breast cancer (p=0.04). Moreover, the relative risk for breast cancer among patients with mastitis was RR: 2.069. Conclusion:Our study showed a relation between mastitis and breast cancer. Mastitis could be a potential risk factor. Further studies with larger number of patients are mandatory in order to confirm this possible relationship.

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Figures

FIGURE 1.
FIGURE 1.
Lactional mastitis
FIGURE 2.
FIGURE 2.
Periductal mastitis
FIGURE 3.
FIGURE 3.
Peau d’orange
TABLE 1.
TABLE 1.
Percentages of patients who developed mastitis
TABLE 2.
TABLE 2.
Association of mastitis with the occurrence of breast cancer
TABLE 3.
TABLE 3.
Relative risk of mastitis and breast cancer
See this image and copyright information in PMC

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