Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Apr;49(4):252-260.
doi: 10.1136/jme-2022-108511. Epub 2022 Dec 21.

Expanded terminal sedation in end-of-life care

Affiliations

Expanded terminal sedation in end-of-life care

Laura Gilbertson et al. J Med Ethics. 2023 Apr.

Abstract

Despite advances in palliative care, some patients still suffer significantly at the end of life. Terminal Sedation (TS) refers to the use of sedatives in dying patients until the point of death. The following limits are commonly applied: (1) symptoms should be refractory, (2) sedatives should be administered proportionally to symptoms and (3) the patient should be imminently dying. The term 'Expanded TS' (ETS) can be used to describe the use of sedation at the end of life outside one or more of these limits.In this paper, we explore and defend ETS, focusing on jurisdictions where assisted dying is lawful. We argue that ETS is morally permissible: (1) in cases of non-refractory suffering where earlier treatments are likely to fail, (2) where gradual sedation is likely to be ineffective or where unconsciousness is a clinically desirable outcome, (3) where the patient meets all criteria for assisted dying or (4) where the patient has greater than 2 weeks to live, is suffering intolerably, and sedation is considered to be the next best treatment option for their suffering.While remaining two distinct practices, there is scope for some convergence between the criteria for assisted dying and the criteria for ETS. Dying patients who are currently ineligible for TS, or even assisted dying, should not be left to suffer. ETS provides one means to bridge this gap.

Keywords: Euthanasia; Pain Management; Palliative Care; Right to Die; Terminal Care.

PubMed Disclaimer

Conflict of interest statement

Competing interests: JS is a Bioethics Committee consultant for Bayer Pharmaceutical. There are no other COI.

Figures

Figure 1
Figure 1
Quality of consciousness at the end of life.
Figure 2
Figure 2
Convergence between the eligibility criteria for VAD, ETS and TS in Victoria. ETS, expanded terminal sedation; TS, terminal sedation; VAD, voluntary assisted dying.

Comment in

References

    1. de Graeff A, Dean M. Palliative sedation therapy in the last weeks of life: a literature review and recommendations for standards. J Palliat Med 2007;10(1):67–85. 10.1089/jpm.2006.0139 - DOI - PubMed
    1. Heijltjes MT, van Thiel GJMW, Rietjens JAC, et al. . Changing practices in the use of continuous sedation at the end of life: a systematic review of the literature. J Pain Symptom Manage 2020;60(4):828–46. 10.1016/j.jpainsymman.2020.06.019 - DOI - PubMed
    1. van Delden JJM. Terminal sedation: source of a restless ethical debate. J Med Ethics 2007;33(4):187–8. 10.1136/jme.2007.020446 - DOI - PMC - PubMed
    1. White BP, Willmott L, Ashby M. Palliative care, double effect and the law in Australia. Intern Med J 2011;41(6):485–92. 10.1111/j.1445-5994.2011.02511.x - DOI - PubMed
    1. McIntyre A. The Stanford Encyclopaedia of Philosophy: Metaphysics Research Lab. In: Doctrine of double effect. Spring, Stanford University, 2019.

Publication types

Substances

LinkOut - more resources