New cuts for CRISPR effectors

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Comment

Darren J Burgess. Nat Rev Genet. 2023 Feb.

. 2023 Feb;24(2):71.

doi: 10.1038/s41576-022-00570-w.

No abstract available

Comment on

RNA-activated protein cleavage with a CRISPR-associated endopeptidase.
Strecker J, Demircioglu FE, Li D, Faure G, Wilkinson ME, Gootenberg JS, Abudayyeh OO, Nishimasu H, Macrae RK, Zhang F. Strecker J, et al. Science. 2022 Nov 25;378(6622):874-881. doi: 10.1126/science.add7450. Epub 2022 Nov 3. Science. 2022. PMID: 36423276 Free PMC article.
RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease.
Kato K, Okazaki S, Schmitt-Ulms C, Jiang K, Zhou W, Ishikawa J, Isayama Y, Adachi S, Nishizawa T, Makarova KS, Koonin EV, Abudayyeh OO, Gootenberg JS, Nishimasu H. Kato K, et al. Science. 2022 Nov 25;378(6622):882-889. doi: 10.1126/science.add7347. Epub 2022 Nov 3. Science. 2022. PMID: 36423304 Free PMC article.

1. Kato, K. et al. RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease. Science 378, 882–889 (2022) - DOI
1. Strecker, J. et al. RNA-activated protein cleavage with a CRISPR-associated endopeptidase. Science 378, 874–881 (2022) - DOI