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. 2022 Nov 25;7(6):2076-2083.
doi: 10.1002/lio2.964. eCollection 2022 Dec.

The relationship between round window and ear canal Cochlear microphonic

Yongqiang Yu  1   2   3   4 , Junping Liu  1 , Jastin Antisdel  3 , Changming Liu  1 , Joshua Sappington  3 , Xiaobin Wang  5 , Yunge Gao  6 , Yanguo Peng  1 , Hui Wang  1 , Zhonghao Lin  1 , Hongguang Ruan  1 , Ruiying Wang  7 , Shuwu Lin  8 , Ming Zhang  4   9   10
Affiliations

The relationship between round window and ear canal Cochlear microphonic

Yongqiang Yu et al. Laryngoscope Investig Otolaryngol. .

Abstract

Hypothesis: Cochlear microphonic recorded at ear canal (CM-EC) can be a substitute for the one recorded at round window (CM-RW).

Background: Almost all clinics do not measure tone-burst evoked CM due to technical difficulty although it can provide more information than click evoked CM. Moreover, clinicians like the CM-EC more than that measured at CM-RW because CM-EC is non-invasive. There is difference between CM-RW and CM-EC, for example, CM-EC is less prominent than CM-RW, therefore, studying tone-burst evoked CM-EC and its relationship with CM-RW are highly significant and can promote the clinical application of CM-EC.

Method: Nine guinea pigs were randomly allocated into three groups, group 1 was not exposed to noise, called normal control. group 2 and group 3 were exposed to the low- (0.5-2 kHz) and high-frequency band-noise (6-8 kHz) at 120 dB SPL for 1 h, respectively. It was difficulty to record low-frequency CM due to severe environmental interruption, in current study the recording technology of tone-burst evoked CM was optimized so that tone-burst evoked CM was measured across full speech frequency (0.5-8 kHz) in the presence of normal hearing and noise induced hearing loss (NIHL).

Results: CM-RW and CM-EC were successfully recorded across speech frequency. Significant reduction in CM amplitude was observed at 0.5 and 2 kHz in group 2, at 6 and 8 kHz in group 3 as compared to group 1, p < .05, indicating that CM amplitude was sensitive to band-noise exposure. Significant correlation between CM-RW and CM-EC was also verified, p < .05.

Conclusion: CM-EC is a useful objective test for evaluation of hearing function; the result of current study supports the clinical application of non-invasive CM-EC.

Keywords: ear canal cochlear microphonic; noise induced hearing loss; round window cochlear microphonic.

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Conflict of interest statement

We declare that there is no competing financial interests in relation to the work described. There is no conflict of interests.

Figures

FIGURE 1
FIGURE 1
The Calculation of CM amplitude. The amplitudes of CM were calculated as the difference between the peak of a given polarity and the peak of the opposite polarity. CM, Cochlear microphonic
FIGURE 2
FIGURE 2
(A) The response pattern of CM‐RW in group 1. (B) The response pattern of CM‐EC in group 1. (C) The response pattern of CM‐RW in group 2. (D) The response pattern of CM‐EC in group 2. (E) The response pattern of CM‐RW in group 3. (F) The response pattern of CM‐EC in group 3. CM‐EC, Cochlear microphonic recorded at ear canal; CM‐RW, Cochlear microphonic recorded at round window
See this image and copyright information in PMC

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